摘要
聚N-异丙基丙烯酰胺具有良好的温敏性能,原子转移自由基聚合(ATRP)技术是合成结构规整性聚合物的有效途径。本文综述了采用ATRP技术合成聚N-异丙基丙烯酰胺的研究进展,并介绍了快速响应PNI-PAM水凝胶的合成方法,以及PNIPAM温敏性凝胶在药物释放、酶的固定、生化物质分离和医用生物高分子材料等方面的应用现状。
Poly(N-isopropylacrylamide)has been widely used in biomedical for its favorable thermosensitivity. In this paper, the latest advance in the synthesis of poly(N-isopropyl-acrylamide)via ATRP technology was summarized,and the application of the poly (N-isopropylacrylamide) gel in drug release and enzymatic immobilization was introduced briefly.
出处
《材料开发与应用》
CAS
2008年第2期61-66,共6页
Development and Application of Materials