应用己酮可可碱及聚烯酮碘预防术后肠粘连的实验研究

An experimental study on preventing postoperative intestinal adhesions by pentoxifylline and povine iodine

为观察己酮可可碱及聚烯酮碘预防术后肠粘连作用，作者采用８０只ＳＤ鼠制成肠粘连模型并分成四组：即对照组，聚烯酮碘组，己酮可可碱组和两药合用组。每组含动物２０只。结果显示各组粘连程度不同，从重到轻依次为对照组，聚烯酮碘组，己酮可可碱组和两药合用组。说明聚烯酮碘与己酮可可碱有预防术后肠粘连作用，两药合用可产生协同作用。

In order to observe the effects of pentoxifylline and povine iodine on preventing postoperative intestinal adhesions (POIA),the authors used eighty SD rats as the models of intestinal adhesions and divided them into four groups:control group,pentoxifylline group,povine iodine group,and combining drugs group Each group contained twenty rats The results showed that the adhesions of each group were different and the consequence of adhesive degree (from serious to slight) was control group,povine iodine group,pentoxifyllin group,and combining drugs group It is demonstrated that pentoxyfilline and povine iodine have significant effects on preventing POIA; and the combination of the two drugs can have a synergetic effect on POIA