安钠咖滥用者的胰腺分泌和C肽及肿瘤坏死因子变化

ALTERATION IN PANCREAS SECRETION,C PEPTIDE AND TUMOR NECROSIS FACTOR OF LONG TIME CAFFEINE SODIUM BENZOATE USE

目的:观察安钠咖滥用者的胰腺分泌和C肽及肿瘤坏死因子变化。方法:应用电化学发光免疫分析法测定36例安钠咖滥用者与14例正常对照血中胰岛素、C肽及肿瘤坏死因子量。结果:安钠咖滥用组与正常对照组比较胰岛素、C肽明显增高(P<0.05),肿瘤坏死因子增高,但在统计学上无差异(P>0.05)。结论:安钠咖滥用者的胰腺分泌和C肽及肿瘤坏死因子升高。

Objective：To observe the alteration in pancreas secretion,C peptide and tumor necrosis factor of long time caffeine sodium benzoate use.Methods：Serum insulin,C peptide and tumor necrosis factor of 36 long time caffeine sodium benzoate users and 14 normal control group were determined by electro-chemistry immunity analytical method.Results：Significant difference was observed in the serum insulin,C peptide of the caffeine sodium benzoate users and the control（P〈0.05）.Rise of tumor necrosis factor was also found in the users but did not show significant difference compared with the control（P〉0.05）.Conclusion：Long time caffeine sodium benzoate use would lead to the rise of pancreas secretion,C peptide and tumor necrosis factor of the users.