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来曲唑治疗绝经后晚期转移性乳腺癌疗效观察 被引量:3

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摘要 目的:观察来曲唑(letrozole)治疗绝经后晚期转移性乳腺癌的疗效及不良反应。方法:20例绝经后晚期转移性乳腺癌患者给予来曲唑口服2.5mg/d,连服8周。结果:20例患者中,完全缓解(CR)0例,部分缓解(PR)3例,占15%,稳定(SD)12例,其中SD≥6个月6例,临床获益(CR+PR+SD≥6个月)9例,占45%;病情进展(PD)5例,占25%;一线治疗7例,有效2例,临床获益4例;二线治疗13例,有效1例,临床获益2例;治疗中无严重不良反应发生。结论:来曲唑治疗绝经后晚期转移性乳腺癌有一定疗效,药物不良反应轻,患者可耐受。
出处 《实用医学杂志》 CAS 2008年第7期1217-1218,共2页 The Journal of Practical Medicine
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