卵巢过度刺激综合征38例临床分析

Clinical anslysis for 38 cases with ovarian hyperstimulation syndrome

目的探讨辅助生育技术中卵巢过度刺激综合征（OHSS）的诱因及临床预防与治疗方法。方法对行促排卵中发生中、重度OHSS38例住院患者进行回顾性分析。结果38例患者均有不同程度的腹胀、恶心呕吐．血液浓缩和腹水。经补充白蛋白、羟乙基淀粉等输液治疗，38例痊愈出院，且羟乙基淀粉可以显著减少白蛋白的用量（羟乙基淀粉组0．76g／kg，右旋糖酐组1．56g／kg）。结论OHSS是促排卵、超排卵引起的严重并发症；静脉滴注白蛋白、腹腔穿刺为治疗OHSS的有效措施；OHSS可治愈。

Objective To Search for the induced factors and therapeutic strategies for ovarian hyperstimu-lation syndrome（OHSS）. Methods 38 cases with OHSS were retrospectively analyzed. Results All cases had symptoms of stomach and intestine, hemachrosis and ascltic fluid. Human serum albumin through intravenous dripping was one of the most successful treatment as plasma expanders through restoration of effective blood volume. Paracentesis was necessary for critical OHSS patients with severe ascites and hydrothorax. Hems could decrease the cost of albumin significantly. Conclusions OHSS was the severe complication of ovarian stimulation. All patients with OHSS got completely recovered through intense care and effective treatment.