肠道平滑肌动力与炎症性肠病研究进展

Update on motility of intestinal smooth muscle in inflammatory bowel disease

肠道平滑肌动力改变与炎症性肠病(IBD)的发病关系得到医学界的重视,并逐渐成为IBD发病机制研究的热点。肠道运动的异常和神经递质的失衡在IBD的发生和进展过程中起了重要作用;白细胞介素能在一定程度上反映肠道运动功能变化。因此,恢复神经递质的失衡并重建肠道动力平衡的策略在IBD治疗过程中有良好的应用前景。

As a new direction in the pathogenesis of inflammatory bowel disease, the role of intestinal motility is being recognized and becoming a hotspot. The abnormity of intestinal motility and the imbalance of the expression of neurotransmitter play an important role in the development and progress of inflammatory bowel disease, they can be reflected via interleukin in some extend, Intervention in the imbalance of the expression of neurotransmitter and rebuilding the balance of intestinal motility should be a prospective strategy for inflammatory bowel disease therapy.