前列腺素E_1治疗肝硬化门静脉高压症46例

CLINICAL ANALYSIS ON TREATING 46 CASES OF CIRRHOTIC PORTAL HYPERTENTION WITH PROSTAGLANDIN E 1

对４６例患者通过观察治疗前后门静脉和脾静脉血流的变化，结果表明前列腺素Ｅ１（ＰＧＥ１）可使门、脾静脉的口径缩小、肝血流量减少，治疗总有效率为８２．６％及８０．４％，副作用少，并探讨其作用机理。

In order to evaluate the efficacy of prostaglanin E 1 in treatment of cirrhotic portal hypertension,the blood flow in portal and spleen veins before and after the treatment was observed by color Doppler.Results showed that a total efficacy of 82.6% was obtained with no obvious ADRs.Its mechanism is briefly discussed.