真菌性角膜溃疡药物治疗体会

The non-surgical therapy of fungal cornea ulcer

目的评价真菌性角膜溃疡非手术治疗的效果。方法对68例68眼真菌性角膜溃疡患者，采用局部、全身药物治疗等方法的疗效进行回顾性分析，总结非手术方法治疗真菌性角膜溃疡的效果。结果68例真菌性角膜溃疡患者经非手术治疗，治愈25只眼，好转19只眼，无效24只眼，复发2只眼。结论非手术治疗方法是治疗真菌性角膜溃疡的一种有效的方法。广谱抗真菌药物多烯类与三唑类药物局部及全身联合治疗真菌性角膜溃疡有效，尤其对溃疡面积小、浸润浅者效果好，复发率低。对于非手术治疗无效的重症患者需行穿透性角膜移植手术治疗。

Objective To summarize curative effect of the non-surgical operations cured the fungal cornea ulcer. Methods 68 inpatients （68 eyes） of the fungal cornea ulcer were treated with medicine locally and systemically.To analyze the curative effect of medication in fungal cornea ulcer. Result The cure rate of non-surgical operation treatment was 36.76%, the improvement rate is 27.94%, the inefficacious rate is 35. 29%, 2 cases were relapsed. Conclusions The non-surgical operation treatment is the effective method of cure the fungal cornea ulcer. Broad spectrum antifungal agents,especially the polyene and triazole ,is efficacious drug to fungal cornea ulcer.The curative effect is conspicuous to the low-grade cases. The refractory cases should be treated with surgical operation.