摘要
实验观察鹿茸多肽(piloseantlerpolypeptide,PAP)对小鼠耐缺氧和抗疲劳能力的影响。实验设立对照组和实验组(PAP低剂量、中剂量和高剂量组),其中实验组灌胃给予高、中、低剂量的PAP,对照组灌胃给予同低剂量PAP组相同体积的生理盐水。连续灌胃30d,常压耐缺氧法观察小鼠存活时间,断头缺氧缺血法观察小鼠张口喘气时间,并观察小鼠爬杆时间、负重游泳时间,测定游泳前、游泳后0min和20min血清乳酸含量的变化。结果显示PAP能显著增加小鼠常压缺氧存活时间、断头喘气时间、爬杆时间和负重游泳时间;并能显著降低游泳后血清乳酸的增加量。说明PAP能够提高小鼠耐缺氧和抗疲劳的能力。
Experimental observation of the effects of pilose antler polypeptide on the ability of mouse anti-anoxia and antifatigue. All of the mice were divided into two groups, each consisting established control group and experimental group （PAP lowdose, medium-dose and high-dose group）, which was given PAP, according to the dose of the experimental group, the control group was given a low dose with the volume of normal saline group. Gavage for 30days, the mice in each group was observed atmospheric anti-anoxia survival time; Decapitated after pant time; Climbing-time and loaded swimming time.And the same time, determination before swimming, swimming 0 minutes and 20 minutes of serum lactate content changes. The results showed that PAP can be significantly increased in mice atmospheric anti-anoxia survival time, decapitated after pant time, climbing-time and loaded swimming time; significantly decreased after swimming the increase in serum lactate. It is concluded that PAP can improve the ability of mouse anti-anoxia and anti-fatigue.
出处
《食品科学》
EI
CAS
CSCD
北大核心
2008年第4期386-388,共3页
Food Science
基金
吉林大学农学部青年基金资助项目(430505010241)
吉林大学农学部大学生科技创新基金项目
