同种异体胎儿骨移植治疗良胜骨肿瘤(附31例报告)

Allogeneic Fetal Bone Graft for the Treatment of Beningn Bone Tumors(A Report of 31 Cases)

为了填充和修复良性骨肿瘤及瘤样病变刮除或切除术后遗留的骨缺损，作者自1990年5月～1996年5月采用经75％酒精浸泡贮存的同种异体胎儿骨移植治疗良性骨肿瘤及瘤样病变31例，取得了良好的效果。术后除5例发生体温变化，平均7天恢复正常体温，1例刀口浅表感染外，其余病例无明显不良反应。术后3周胎儿骨开始吸收，5周腔壁处有新骨生长影象，平均9个月肿瘤腔完全由新生骨代替。因此，作者认为胎儿骨具有制做及贮存方法简易、“爬行替代”作用快、骨诱导能力强、免疫排斥反应小等优点，是一种良好的植骨材料。

In outer to repair bone defects of benign bone tunors and tumor - like lesions after resection from May 1990 to May 1996, the author conducted a study of using alcohol - preserved allogeneic fetal for as graft to treat 31 cases of bening bone tumor and tumor - like lesions. 5 cases had body tenpreture above 38 .5℃ postoperatively with an average 7 days to return to normal, and 1 case got superficial infection in the incision. Other cases did not have and obvious harmful reaction. The grafted bone began to be absorbed 3 weeks after operation and the growth of new bone on the cavity walls of bone defects could be seen in the roentgenograph 5 weeks after operation. In average time of 9 months, the cavities occupied by the tumors preoperatively were filled with new bone. So we got the conclusion that the creeping substitution of felal bone developed Very rapidly, the ability of induced osteogensis was great and the immunorejechon to fetal bone of the recipient was not obvious, the preparation and storage of fetal bone was very simple, Fetal bone can serve as a good graft.