维药睡莲花中的黄酮醇苷类成分分析

Flavonol Glycosides from the Flowers of Nymphaea Candida

目的对维药睡莲花的黄酮醇苷类成分进行研究。方法采用硅胶、聚酰胺和Sephadex LH-20柱进行分离,利用理化性质和波谱学方法鉴定化合物的结构。结果分得六个黄酮醇苷类化合物,分别为黄芪苷(Ⅰ)、槲皮素3-O-甲基-3′-O-β-D-吡喃木糖苷(Ⅱ)、槲皮素3′-O-β-D-吡喃木糖苷(Ⅲ)、异槲皮苷(Ⅳ)、山萘酚3-O-β-D-芸香糖苷(Ⅴ)、芦丁(Ⅵ)。结论化合物Ⅰ、Ⅳ、Ⅵ为首次从该植物中分离得到,其中化合物Ⅳ为首次从该属植物中分离得到。

OBJECTIVE To isolate and determine chemical constituents from Nymphaea candida Presl. METHODS Six compounds were isolated and purified by extraction and different kinds of column chromatography. The structures were determined on the basis of spectral analysis. RESULTS The structures were elucidated as astragalin （Ⅰ）, quercetin 3-methyl ether 3＇-O-β-D-xylopyranoside （Ⅱ）, quercetin Y-O-β-D-xylopyranoside （ Ⅲ）, isoquercitrin （ Ⅳ）, kaempferol - 3-O-rutinoside （Ⅴ） and rutin （Ⅵ）. CONCLUSION Compound Ⅰ, Ⅳ and Ⅵ are obtained from this plant for the first time, and compound Ⅳ were isolated from Nymphaea genus for the first time.