补肾化瘀祛痰法治疗多囊卵巢综合征的临床研究

Clinical Study on Bushen Huayu Qutan Treatment for PCOS

目的探讨以补肾化瘀祛痰法治疗多囊卵巢综合征(PCOS)对睾酮(T)、空腹胰岛素(INS)等的调节作用,寻求治疗本病的中医药方法。方法选取70例非高血糖伴胰岛素抵抗的PCOS患者,随机分成中药补肾化瘀祛痰法治疗组(40例)和二甲双胍对照组(30例),观察两组病例T和空腹INS等治疗前后的变化情况。结果治疗组和对照组临床总有效率分别为70%和66.7%,有显著性差异(P<0.05)。结论补肾化瘀祛痰法是治疗伴胰岛素抵抗的PCOS的有效途径。

OBJECTIVE To observe the effect of Bushen Huayu Qutan treatment on regulating serum level of testosterone （T） , fasting insulin （INS） in patients with polycystic ovary syndrome （PCOS） accompanied by insulin resistance （IR） , and to explore the method of traditional Chinese medicine in treating PCOS. METHODS Seventy patients with PCOS-IR but non-higher blood glucose were randomly classified into the treated group with Chinese herbal medicine Bushen Huayu Qutan（ group A,40 cases）and the control group with metformin（ group B ,30 cases）. Clinical symptoms and signs improvements and serum T、INS levels were analyzed before and after therapy. RESULTS The total effective rate of group A was 70% , higher than that of group B （ 66. 7%, P 〈 0.05 ）. CONCLUSION Bushen Huayu Qutan treatments is effective in treating PCOS-IR.