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2型糖尿病血清淀粉样蛋白A水平与颈总动脉内中膜厚度相关 被引量:12

Association between serum amyloid A and intima-media thickness of common carotid artery in patients with type 2 diabetes
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摘要 169例短病程2型糖尿病患者,根据大动脉内中膜厚度(IMT)分为动脉粥样硬化(AS)组和非AS组,测定血清淀粉样蛋白A(SAA)水平,结果显示2型糖尿病组SAA水平较对照组高,AS组高于非AS组,并与年龄、体重指数、腰臀比及颈总动脉IMT呈正相关;年龄、C反应蛋白及SAA是影响颈总动脉IMT的相关因素。 A total of 169 patients with short-duration type 2 diabetic mellitus (DM) were divided into atherosclerosis (AS) group and non-AS group according to the intima-media thickness (IMT) of three conducting arteries. The level of serum amyloid A (SAA) was assayed by ELISA. The resuhs showed that SAA level of type 2 DM patients increased significantly, patients in AS group showed higher SAA level than that in non-AS group, and SAA level was positively correlated with age, body mass index, waist hip ratio and IMT of common carotid artery. Age, C-reactive protein and SAA level are the major risk factors for IMT of common carotid artery.
出处 《中华内分泌代谢杂志》 CAS CSCD 北大核心 2008年第2期188-189,共2页 Chinese Journal of Endocrinology and Metabolism
基金 “十五”国家科技攻关课题资助项目(2001BA702B01) 辽宁省科技厅科技攻关项目(2002225003-6) 辽宁省教育厅高等学校科学研究项目(202203266)
关键词 血清淀粉样蛋白A 糖尿病 2型 动脉内中膜厚度 Serum amyloid A Diabetes mellitus, type 2 Intima-media thickness
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