摘要
目的:观察消瘤胶囊对下肢静脉曲张患者血清丙二醛(MDA)、超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)的影响。方法:对36例下肢静脉曲张患者采用消瘤胶囊治疗。疗程2月。观察治疗前后血清MDA、SOD、GSH-Px变化情况。结果:失访4例,治疗前存在血清高MDA水平和低SOD、GSH-Px水平,治疗后MDA降低,SOD、GSH-Px升高,治疗前后比较,差异均有显著性意义(P<0.05)。结论:消瘤胶囊可调节下肢静脉曲张患者血清MDA、SOD、GSH-Px水平;推测拮抗氧自由基损伤可能是其治疗下肢静脉曲张的机理之一。
Objective:To observe the effect of Xiaoliu Capsule (XC)on serum malondialdehyde (MDA),superoxide dismutase (SOD)and glutathione perexidase (GSH-Px)in patients with lower extremity varicosity (LEV).Methods:Thirty-six LEV patients were treated with XC for 2 months.The chants of serum levels of MDA,SOD and GSH - Px were observed More end after treatment.Results:There were 4 patients loss of follow-up.Serum MDA level was high,and SOD and GSH - Px levels were lower before treatment.After treatment,MDA level was decreased, and SOD and C,SH - Px levels were increased,the differences being sisnificant (P<0.05 compared those before treatment).Conclusion:XC regulates the serum levels of MDA,SOD and GSH - Px in patients with lower extremity varicosity,which is one of its therapeutic mechanisms for the treatment of lower extremity varicosity.
出处
《新中医》
CAS
北大核心
2008年第5期43-44,共2页
New Chinese Medicine
基金
上海颜德馨中医药基金会资助科研课题项目(编号:05-001-6)
