细胞疗法治疗股骨头缺血性坏死的研究进展
摘要
股骨头缺血性坏死的治疗是目前临床工作面临的难题,其研究受到广泛关注。股骨头缺血性坏死治疗的目的是保存股骨头,避免或延缓全髋关节置换。髓芯减压术是治疗早期股骨头缺血性坏死最常用的方法,它不仅可以降低骨内压力,还可为生物活性材料、细胞等物质的植入创造条件。目前使用较多的移植物包括:血管化和非血管化骨移植物,同种异体和合成的骨替代材料,骨源性和血管源性生长因子以及各种类型的干(祖)细胞。
出处
《中华骨科杂志》
CAS
CSCD
北大核心
2008年第5期424-427,共4页
Chinese Journal of Orthopaedics
参考文献38
-
1Schachinger V, Erbs S, Elsasser A, et al. Intracoronary bone marrow-derived progenitor ceils in acute myocardial infarction. N Engl J Med, 2006, 355: 1210-1221.
-
2Collins SD, Baffour R, Waksman R. Cell therapy in myocardial infarction. Cardiovasc Revasc Med, 2007, 8: 43-51.
-
3Schuleri KH, Boyle AJ, Hare JM. Mesenchymal stem cells for cardiac regenerative therapy. Handb Exp Pharmacol, 2007, 180: 195- 218.
-
4Tateishi-Yuyama E, Matsubara H, Murohara T, et al. Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial. Lancet, 2002, 360: 427-435.
-
5Hernigou P, Beaujean F, Lambotte JC. Decrease in the mesenchymal stem-cell pool in the proximal femur in corticosteroid-induced osteoneerosis. J Bone Joint Surg (Br), 1999, 81: 349-355.
-
6Lee JS, Lee JS, Roh HL, et al. Alterations in the differentiation ability of mesenchymal stem ceils in patients with nontraumatic osteonecrosis of the femoral head: comparative analysis according to the risk factor. J Orthop Res, 2006, 24: 604-609.
-
7Sottile V, Thomson A, McWhir J. In vitro osteogenic differentiation of human ES cells. Cloning Stem Cells, 2003, 5: 149-155.
-
8Slack JM. Stem cells in epithelial tissues. Science, 2000, 287: 1431-1433.
-
9Liechty KW, Mackenzie TC, Shaaban AF, et al. Human mesenchymal stem ceils engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Nat Med, 2000, 6: 1282- 1286.
-
10Ikeguchi R, Kakinoki R, Aoyama T, et al. Regeneration of osteonecrosis of canine scapho-lunate using bone marrow stromal cells: possible therapeutic approach for Kienbock disease. Cell Transplant, 2006, 15: 411-422.
二级参考文献55
-
1付小兵,方利君,王玉新,孙同柱,程飚.骨髓间充质干细胞自体移植提高猪皮肤创面修复质量的初步研究[J].中华医学杂志,2004,84(11):920-924. 被引量:37
-
2[1]Montma, Hungerford DS, Maryland B. Current concepts review. Surg 1995 ;77A: 495.
-
3[3]Jones JP. Intravascular coagulation and osteonecrosis. Clin Orthop 1992; (277): 41-53.
-
4[5]Islam A, Glomski C, Hendenson ES. Endothelial cells and hematopoiesis: a light microscopic study of fetal, normal, and pathologic human bone marrow in plastic-embedded sections.Anat Res 1992 ;233(3) :440-452.
-
5[6]Diaz-Flores L,Gutierrez R,Lope ZA,et al. Pericytes as a supplementary source of osteoblasts in periosteal osteogenesis. Clin Orthop 1992; (275): 280-286.
-
6[7]Favas M. Priner on the metabolic disease and disorders of mineral metabolism. New York: Rava Press,1993:50-60.
-
7[8]Matsui M, Saito S, Ohzono K,et al. Experimental steroid-induced osteonecrosis in adult rabbits with hypersensitivity vasculitis. Clin Orthop 1992; (277) :61-72.
-
8[9]Berry L, Grant ME, McClure J, et al. Bone-marrow-derived chondrogenesis in vitro. J Cell Sci 1992; 101 (Pt 2):333-342.
-
9[10]Noel D,Djouad F,Jorgense C. Regenerative medicine through mesenchymal stem cells for bone and cartiliage repair. Curr Opin Investig Drugs 2002;(7):1000-1004.
-
10[11]Jiang Y, Jaliagirdar BN, Reinhard RL, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 2002; 418(6893):41-49.
共引文献53
-
1张波,杨述华,张宇坤,孙志博,许伟华,叶树楠.Co-culture of Mesenchymal Stem Cells with Umbilical Vein Endothelial Cells under Hypoxic Condition[J].Journal of Huazhong University of Science and Technology(Medical Sciences),2012,32(2):173-180. 被引量:3
-
2李克涛,王玉娥,龚跃昆,李彪,刘建兴.成人股骨头缺血性坏死的研究前景[J].昆明医科大学学报,2009,32(S2):150-153. 被引量:3
-
3孙宝东,吴鸣,闫迎军,张海林,乔群.股前外侧带蒂皮瓣修复外阴癌切除术后皮肤软组织缺损[J].中华医学杂志,2005,85(48):3442-3443. 被引量:12
-
4杨晓凤,王红梅,许忆峰,张轶斌,徐波,吴雁翔,吕欣,林慧丽.经动脉骨髓干细胞移植治疗股骨头坏死63例[J].中国临床康复,2006,10(13):3-5. 被引量:51
-
5杨建平,徐燕,王黎明.骨髓间充质干细胞治疗股骨头坏死的进展[J].中国组织工程研究与临床康复,2007,11(15):2955-2959. 被引量:16
-
6金红婷,童培建.骨髓基质干细胞治疗股骨头坏死的研究和应用[J].浙江中医药大学学报,2007,31(3):397-398.
-
7史沛,茹凤娟,郭春雨,胡宗杰,臧西超.经动脉骨髓干细胞移植结合介入治疗股骨头缺血性坏死[J].中国组织工程研究与临床康复,2007,11(37):7345-7348. 被引量:6
-
8王天胜,刘永灿,郭利,丁海蛟,王法,张英霞,杨晓凤,王红梅.干细胞移植在中晚期股骨头坏死治疗过程中的应用[J].中国组织工程研究与临床康复,2008,12(3):505-508. 被引量:12
-
9杨晓凤,王红梅,许忆峰,张轶斌,吴雁翔,吕欣,吕乃武,单鸿,马淑彦.干细胞移植改善股骨头坏死缺血状态的实验及临床效应:20只模型兔及188例患者资料分析(英文)[J].中国组织工程研究与临床康复,2008,12(8):1558-1562. 被引量:15
-
10单鸿,杨晓凤,王红梅,吴雁翔,张轶斌,许忆峰,吕乃武.自体骨髓干细胞移植治疗创伤性股骨头坏死24例[J].医学信息,2008,21(4):534-535. 被引量:3
-
1王正,黄相杰,姜红江.股骨头缺血性坏死的髓芯减压及其相关研究进展[J].中医正骨,2006,18(10):78-79. 被引量:7
-
2吴基铨.治疗骨折不愈合的植骨术[J].中国创伤骨科杂志,2000,2(3):179-184. 被引量:1
-
3孙磊,胡蕴玉,王玉清,陆裕朴,宁志杰,吕荣.不同处理的骨移植物的骨诱导活性比较研究[J].中国矫形外科杂志,1995,2(4):262-263. 被引量:6
-
4许敏.介入联合骨髓芯减压术治疗股骨头缺血性坏死的术中配合[J].家庭护士(专业版),2008,6(19):1747-1748. 被引量:1
-
5李守宏,庞光明,陈建钢,刘茁.非血管化方式修复下颌骨缺损远期疗效的临床评价[J].现代口腔医学杂志,2005,19(6):660-660.
-
6王保民.中西医结合治疗早期股骨头缺血性坏死的临床分析[J].中外医疗,2012,31(22):117-117.
-
7徐正良,张长青.细胞疗法治疗股骨头坏死研究进展[J].国际骨科学杂志,2012,33(3):178-180.
-
8张长青.股骨头缺血性坏死治疗及其争议[J].同济大学学报(医学版),2009,30(2):1-5. 被引量:4
-
9陆文忠,凌尚准.山区27例/34髋股骨头缺血性坏死治疗的临床观察[J].右江医学,2002,30(1):15-16.
-
10赵泉,张柘.全髋关节置换术治疗股骨头缺血性坏死的效果观察[J].中国处方药,2016,14(11):113-114. 被引量:1