中药药性研究概论

Speculating about scientific investigation on nature of Chinese materia medica

当今中药药性研究热潮越来越高。在回顾原有研究的基础上,对中药药性研究存在的问题进行反思,指出中药药性研究在近期内要取得重大突破,应进一步凝练研究目标,理清研究思路,规范研究方法。寒热药性可作为首要突破口;建立寒热药性的客观评价方法,阐明寒热药性的客观真实性将是中药药性理论研究的首要关键科学问题之一。首次提出并建立了基于还原整合和热力学表达的中药药性研究模式和方法。

The scientific investigation on the nature of Chinese materia medica （CMM） has stepped into a critical moment. In this paper, the objectivity of the CMM nature and some other relevant existing problems are discussed based on retrospective and prospective analyses. It could be concluded that there is a duality about the objective connotation of the CMM nature. In order to get a significant breakthrough in near future in the scientific investigation on the CMM nature, the goal, strategy, and methodology should be reconsidered and adjusted. Cold and heat, the most radical and important elements of the CMM nature should be treated as the most principal task in the field. The key scientific issues can be refined to establish a set of objective and scientific evaluating system for the CMM nature, and to elucidate its objective connotation. In view of restoration to integration as well as thermodynamic expression, a set of new ideas and methods for the investigation on the CMM nature has been put forward in this paper.