1Oh SB, Tran PB, Gillard SE,et al.Chemokines and glycoprotein 120 produce pain hyper- sensitivity by directly exciting primary nociceptive neurons[J].J Neurosci,2001,116: 29-39.
2Heyer G,Ulmer FJ,Schmitz J,et al.Histamine-induced itch and alloknesis(itchy skin) in atopic eczema patients and controls[J].Acta Derm Venereol,1995,75: 348-352.
3Rukwied R, Lischetzki G,McGlone F,et al.Mast cell mediators other than histamine induce pruritus in atopic dermatitis patients:a dermal microdialysis study[J].Br J Dermatol,2000,142: 1114-1120.
4Pincelli C.Nerve growth factor and keratinocytes:a role in psoriasis[J].Br J Dermatol,2000,10: 85-90.
5Drake LA,Fallon JD,Sober A.Relief of pruritus in patients with atopic dermatitis after treatment with topical doxepin cream[J].J Am Acad Dermatol,1994,31: 613-616.
6Yosipovitch G, Sugeng MW, Chan YH,et al.The effect of topically applied asprin on localized circumscribed neurodermatitis[J].Acta Derm Dermatol,2001,45: 910-913.
7Miller MJ, Vergnolle N,McKnight W,et al.Inhibition of neurogenic inflammation by the Amazonian herbal medicine sangre de grado[J].J Inves Dermatol,2001,117: 725-730.
8Bergasa NV, Alling DW,Talbot TL,et al.Oral nalmefene therapy reduces scratching activity due to pruritus of cholestasis:a contolled study[J].J Am Acad Dermatol,1999,41: 431-434.
10Steinhoff M, Vergnolle N, Young SH,et al. Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism[J].Nat Med,2000,6: 151-158.
1Ikoma A,Steinhoff M,Schmelz M,et al. The neurobiology of itch[ J]. Nat Rev Neurosci,2006,7(7) :535-547.
2Schmalz M, Sehmidt R, Bickel A, et al. Specific C-receptors for itch in human skin[J]. J Neurosci, 1997 (20) , 17 : 8003-8008.
3Schmelz M, Schmidt R,Weidner C, et al. Chemical response pattern of different classes of C-nociceptors to pruritogens and algogens [ J ]. J Neurophysiol, 2003,89 ( 5 ) : 2441-2448.
4Johanek LM, Meyer RA, Hartke T, et al. Psychophysical and physio- logical evidence for parallel afferent pathways mediating the sensation of itch [ J ] J Neurosci, 2007,27 (28) :7490-7497.
5Ikoma A, Rukwied R, Stander S, et al. Neurophysiology of pruritus : in- teraction of itch and pain [ J ]. Arch Dermatol, 2003,139 ( 11 ) : 1475- 1478.
6Papoiu AD, Coghill RC, Kraft RA, et al. A tale of two itches. Common features and notable differences in brain activation evoked by cowhage and histamine induced itch [ J ]. Neurolmage, 2012,59 ( 4 ) : 3611- 3623.
8Davidson S, Giesler GJ. The multiple pathways for itch and their inter- actions with pain[ J]. Trends Neurosci,2010,33(12) :550-558.
9Davidson S, Zhmag X, Khasabov SG, et al. Relief of itch by scratching : state dependent inhibition of primate spinothalamic tract neurons [J]. Nat Neurosci ,2009,12 ( 5 ) : 544-546.
10Papoiu AD, Nattkemper LA, Sanders KM, et al. Brain' s reward cir- cuits mediate itch relief: a functional MRI study of active scratching[J]. PLoS One,2013,8(12) :e0082389.
