部分性脾栓塞术对门脉高压性胃病的影响

Affection of Portal Pypertensive Gastropathy by Partial Splenic Embolization

目的寻求一种新的、安全有效,为目前临床上治疗门脉高压性胃病的治疗方法。方法本组49例患者,被分为治疗组28例门脉高压性胃病患者,对照组21例门脉高压性胃病患者。治疗组采用经皮穿刺股动脉插管行部分性脾动脉栓塞术,以观察两组门静脉、脾静脉的变化,食道静脉曲张程度,胃粘膜的改变。结果28例门脉高压性胃病的患者行PSE术后,可观察到其门静脉、脾静脉均有回缩。食道静脉曲张,胃黏膜的情况可见7例明显改善,19例有改善,2例无变化。对照组仅2例改善,8例稳定,11例恶化。部分性脾栓术改善门脉高压性胃病的总有效率85.71%,对照组总有效率9.52%,有显著差异(P<0.01)。结论部分性脾动脉栓塞对于治疗门脉高压性胃病,食道静脉曲张,安全有效,值得推广应用。

Objective To search for a new ,safe and effective method ,so as to treat portal hypertensive gastropathy.Methods 49 cases were divided into two group：the treatment group 28 cases,the control group 21eases.the treatment group accepted PSE,the control group underwent routine treatment.The changing of PV,SV,esophageal varices and gastric mucosa of the two group were recorded and compared. Results The PV,SV retracted in all treatment cases after PSE.In 7 cesos of the treatment group ,the esophageal varices and gastric mucosa were obviously ameliorated,19 cases were ameliorated,2 cases no changes.In the control group, 2 cases were ameliorated,8 cases no changes,It cases were worse. Effective ratio in treatment group was 85.71% ,Effective ratio in control group was 9.52%,showing significant statistical difference（P〈0.01）. Conclusion PSE can ameliorate esophageal varices and gastric mucosa ,and was safe, effective,and worthy to be recommended.