胶质肉瘤临床研究进展

Advances in the Research of Gliosarcoma

胶质肉瘤(Gliosarcoma,GS)是一种罕见的中枢神经系统原发恶性肿瘤。GS细胞经免疫组织化学染色后,可形成胶质母细胞瘤与恶性纤维组织细胞瘤两种瘤巢团状区互相交错的图像。GS发病急剧,进展迅速,颅外转移较普通胶质瘤多见。手术切除肿瘤是本病最有效的治疗手段。GS对常规放、化疗不敏感,但当出现肿瘤颅外转移时,可作为有益的辅助治疗。

Gliosarcoma （GS） is a rare type of primary malignant tumor of the central nervous system. Immunohistochemistry shows an interlacing appearance of nidus of glioblastoma and malignant fibrous histiocytoma. GS is characteristic of sudden occurrence and rapid progression, with a higher incidence of extracranial metastases than neurogliocytoma. Surgery is the most effective treatment. GS is not sensitive to conventional radiotheraphy or chemotherapy. But both the above treatment are helpful for GS patients with extracranial metastases.