急性呼吸窘迫综合征预后相关因素分析

Analysis of Prognostic Risk Factors of Acute Respiratory Distress Syndrome

目的探讨急性呼吸窘迫综合征(ARDS)不良预后的相关因素。方法收集45例ARDS患者的临床资料,其中存活组21例,死亡组24例,比较两组患者APACHEⅡ评分、慢性疾病史、确诊时间、清蛋白水平间的差异。结果两组患者有无慢性病史、APACHEⅡ评分、ARDS确诊时间和清蛋白水平间差异均有统计学意义(P<0.05)。结论ARDS患者合并有慢性疾病史,诊断时间晚,重度低清蛋白血症时提示预后不良。

Objective To study risk factors of high mortality in acute respiratory distress syndrome. Methods The clinical data of 47 patients in ten years including APACHE Ⅱ score, history of chronic disease, hypoalbuminemia were analyzed and compared with mortality. Results Nonsurvivors group was significantly higher in combining history of chronic disease （83.3%） , same to time of diagnosis; there was no significane between albuminemia≤20 g/L and 20 -28 g/L, while group 〉i 28 g/L had higher mortality than group ≤20 g/L （ P 〈 0. 05 ）. Conclusion We should pay more attention to factors about history of chronic disease, time of diagnosis, hypoalbuminemia in ARDS.