1591例普外科住院患者合理用药监测分析

Prescription Order Analysis of 1591 General Surgical Inpatients with Prescription Automatic Screening System

目的了解住院患者的合理用药情况。方法应用PASS软件进行药物相互作用分析。结果调查涉及1591例患者的32976条住院医嘱,不合理用药医嘱有1556条,主要表现在药物剂量审查、药物相互作用、注射液体外配伍、给药途径监测4个方面,其中抗生素应用不合理医嘱有266条(17.10%)。结论临床医药工作者应互相配合、沟通,根据临床实际情况和患者的个体差异制订合理的用药医嘱,尽量减少用药品种,避免不合理用药。

Objective To understand the current drug utilization for inpatients. Methods Prescription Automatic Screening System（PASS） was used for investigation of possible drug interactions. Results 32 976 prescription orders of 1 591 inpatients were analyzed. There were 1 556 irrational prescription orders. The irrational prescription orders directed mainly for drug dose review, drug interactions, liquid injection compatibility and routes of administration monitoring. Among them, 266（17. 10% ） were irrational prescription orders for antibiotics usage. Conclusion In order to avoid adverse reactions, the prescription should follow the principle of rational drug use, and the number of the drugs should be prescribed as few as possible.