广西14县市人体华支睾吸虫病流行纵向观察

Longitudinal observation on the prevalence and variation of human Clonorchiasis infection in 14 counties in Guangxi

目的了解广西13年间人体华支睾吸虫病流行变化情况。方法1989年按不同地理方位及经济水平分层随机抽取14县市作人体华支睾吸虫感染情况调查,2002年再在相同县市作同样调查,比较两次调查结果,观察华支睾吸虫病纵向变化;用Kato-Katz法检查粪便华支睾吸虫卵;查获虫卵者作克粪便虫卵(EPG)计数。结果两次调查各查36304人和21644人,人群感染率分别为1.63%(592/36304)和5.16%(1116/21644)。2002年与1989年相比,人群总感染率上升了2.17倍,其中女性上升2.66倍,男性上升1.80倍,学前儿童上升5.88倍;轻度感染所占比重由第一次调查的73.14%下降到55.91%,而中、重和超重度的比例分别上升到34.32%、6.01%和3.76%。结论经两次调查,广西华支睾吸虫病流行呈上升趋势,应在重点地区对重点人群开展有针对性的防治工作。

Objective To investigate longitudinally the prevalence of Clonorchiasis in Guangx. Methods Two surveys were carried out in the year of 1989 and 2002. The sites and counties of survey were selected by stratified sampling considering geography and economy levels and totally 14 counties were sampled. The Kato - Katz thick smear was used for fecal examining. Eggs per gram of feces （EPG） of Clonorchis sinensis were counted. Results Totally 36 304 stool samples were examined in the first survey （ 1989 ） and 21 644 stool samples in the second （2002）. The prevalence in the second survey was 5. 16% （ 1 116/21 644）, which was 3.17 times of that of the first 1.63% （592/36 304）. There a 3.66 and a 2.8 folds sharply increase in the infection of females and males were observed. The Comparatively, The highest rise of 5.88 times in infection in preschool children was noticed. On the basis of EPG, the rate of Light infection decreased from 73.14% in 1989 to 55.91% in 2002,while the rates of the moderate, heavy and super - heavy infection were increased by 34.32%, 6.01% and 3.76% respectively. Conclusion The prevalent trend of C. sinensis in Guangxi Zhuang Autonomous Region is increasing, indicating that more intensified control strategies should be made.