瘢痕疙瘩的治疗研究进展
被引量:51
Recent developments in treatment and research of keloid
摘要
瘢痕疙瘩是一种过多胶原沉积导致的纤维增生性疾病,它常在易感人群中发生,为一种超过损伤边界的皮肤或角膜瘢痕。至今为止,瘢痕疙瘩的治疗仍很复杂和困难。目前认为,多种治疗方法的联合应用是最有效和最安全的治疗策略。本文即对瘢痕疙瘩的治疗研究进展综述如下。
出处
《中国美容医学》
CAS
2008年第4期610-613,共4页
Chinese Journal of Aesthetic Medicine
参考文献32
-
1Kauh YC, Rouda S, Mondragon G, et al. Major suppression of pro-alphal (Ⅰ) typeⅠ collagen gene expression in the dermis aider keloid excision and immediate intrawound injection of triamcinolone acetonide[J]. J Am Acad Dermatol, 1997,37(4):586-589.
-
2Boyadjiev C,Popchristova E,Mazgalova J.Histomorphologic changes in keloids treated with Kenacort[J].J Trauma, 1995,38(2):299-302.
-
3Rosen DJ,Patel MK,Freeman K, et al.A Primary protocol for the management of ear keloids: results of excision combined with intraoperative and postoperative steroid injections [J].Plast Reconstr Surg,2007,120(5): 1395-1400.
-
4Donker P. Head and Neck Keloid: Treatment by Core Excision and Delayed Intralesional Injection of Steroid [J].J Oral Maxillofac Surg, 2007,65(7): 1292-1296.
-
5Teelucksingh S,Balkaran B,Ganeshmoorthi A,et al. Prolonged childhood Cushing's syndrome secondary to intralesional triamcinolone acetonide[J]. Ann Trop Paediatr,2002,22(1):89-91.
-
6Luo S,Benathan M,Raffoul W,et al.Abnormal balance between proliferation and apoptotic cell death in fibroblasts derived from keloid lesions[J]. Plast Reconstr Surg, 2001,107( 1):87-96.
-
7Kal HB,Veen RE.Biologically effective doses of postoperative radiotherapy in the prevention of keloids. Dose-effect relationship. Strahlenther Onkol JT- Strahlentherapie und Onkologie:Organ der Deutschen Rontgengesellschaft,2005,181 (11):717-723.
-
8Van de Kar AL, Kreulen M, van Zuijlen PP,et al.The results of surgical excision and adjuvant irradiation for therapy-resistant keloids: a prospective clinical outcome study[J]. Plast Reconstr Surg, 2007,119(7):2248-2254.
-
9Ogawa R,Mitsuhashi K,Hyakusoku H,et al.Postoperative electron-beam irradiation therapy for keloids and hypertrophic scars: Retrospective study of 147 cases followed for more than 18 months [J].Plast Reconstr Surg, 2003,111(2):547-553.
-
10Ragoowansi R,Comes PG,Moss AL,et al.Treatment of keloids by surgical excision and immediate postoperative single-fraction radiotherapy[J].Plast Reconstr Surg,2003,111(6): 1853-1859.
二级参考文献17
-
1鲁峰 高建华 黎小间.病理性瘢痕和正常皮肤中成纤维细胞间缝隙连接通讯的差异[J].解放军医学杂志,2000,15(2):150-2.
-
2Luo S,Benathan M,Raffoul W,et al. Abnormal balance between proliferation and apoptotic cell death in fibroblasts derived from keloid lesions [ J ]. Plast Reconstr Surg, 2001, 107( 1 ): 87-96.
-
3Zoppi RA,Ciontant S,Duek EAR, et al. Porous poly (L-lactide)films obtained by immersion precipitation process: morphology,Phase separation and culture of VERO cell [J]. Polymer, 1999, 40:3275-89.
-
4Peretti GM, Randolph MA, Villa MT, et al. Cell-based tissueengineered allogeneic implant for cartilage repair [J]. Tissue Eng,2000, 6(5): 567-76.
-
5Shea LD, Wang D, Franceshi RT, et al. Engineered bone development from a pre-osteoblast cell line on three-dimensional scaffolds[J]. Tissue Eng, 2000, 6(6): 605-17.
-
6Liu K, Yang Y,Mansbrige J. Comparison of the stress response to cryopreservation in monolayer and three-dimensional human fibroblast cultures: stress proteins, MAP kinases, and growth factor gene expression [J]. Tissue Eng, 2000, 6(5): 539-54.
-
7Sjiki T, Iwata H, Peak HJ, et al. Transmission electron microscopic study ofhepatocytes in bioartificial liver[J]. Tissue Eng, 2000, 6(6):627-640.
-
8Kim BS,Mooney DJ. Development of biocompatible synthetic extracellular matrices for tissue engineering [J]. Trends Biotechnol,1998, 16: 224-30.
-
9Mikos AG, Thorsen A J, Czerwonka LA,et al. Preparation and characterization ofpoly (L-lactic acid) foams[J]. Polymer, 1994, 35: 1068-77.
-
10Puelacher WC, Wisser J, Vacanti CA, et al. Temporomandibular joint disc replacement made by tissue engineered growth of cartilage[J]. J Oral Maxillofac Surg, 1994, 52(11): 1172-7.
共引文献2
-
1李晓伟,刘宏亮,武继祥.病理性瘢痕动物模型的研究进展[J].实验动物科学,2009,26(2):46-49. 被引量:5
-
2张永存,王亮,鲁晋,周浩,唐洪泰.动物模型在烧伤研究中的应用及研究进展[J].中华烧伤杂志,2019,35(9):692-696. 被引量:4
同被引文献455
-
1雷情,张春连,申晓.瘢痕疙瘩手术联合术后放射线治疗对瘢痕增生的影响[J].疾病监测与控制,2022,16(3):209-211. 被引量:3
-
2程晓桃,梁杰,邱晓莉.弹性织物压迫伤口预防增生性瘢痕的效果观察[J].中国临床康复,2004,8(20):3952-3952. 被引量:4
-
3章建林,林子豪,江华,袁湘斌,赵耀忠,吴建明,朱晓海,吴宏.增生性瘢痕组织中TNF-α基因的表达及其意义[J].第二军医大学学报,2005,26(1):48-50. 被引量:8
-
4A. H. Hlscher.Introduction[J].The Chinese-German Journal of Clinical Oncology,2004,3(4):199-200. 被引量:2
-
5刘树铮.低水平辐射对健康的影响[J].核技术,1994,17(6):381-384. 被引量:12
-
6聂学,张彬宇,邢金霞.硅凝胶膜加弹力绷带联合应用治疗增生性瘢痕[J].中国临床康复,2005,9(10):197-197. 被引量:5
-
7章建林,林子豪,江华,袁相斌,赵耀中,吴建明,朱晓海,吴宏.增生性瘢痕组织中TNF-α mRNA的动态表达及临床意义[J].中华整形外科杂志,2004,20(1):57-59. 被引量:11
-
8惠俐,王连唐,杨峥.微晶磨削术修复皮肤浅表性瘢痕[J].中华整形外科杂志,2005,21(3):194-196. 被引量:17
-
9王巧君,王英彩,刘习敏,刘巍,赵红芳.弹力加压时间对大腿供皮区瘢痕形成的影响[J].中国临床康复,2005,9(18):179-179. 被引量:12
-
10刘炳兰,于风娜.康瑞保治疗增生性瘢痕的临床观察[J].现代医药卫生,2005,21(12):1522-1522. 被引量:4
引证文献51
-
1孟凡军,张学诚,赵月荣.瘢痕内切除瘢痕瓣回植联合药物注射治疗瘢痕疙瘩[J].中国美容医学,2008,17(11):1681-1682. 被引量:3
-
2赵欣欣,黎志明.放射性治疗在瘢痕疙瘩治疗上的发展[J].中国美容医学,2008,17(11):1706-1709. 被引量:2
-
3胡启翔,王慧英,王颖艳,王建军.复春散Ⅱ号与曲安奈德联合应用治疗瘢痕疙瘩[J].中国美容医学,2008,17(12):1806-1806. 被引量:1
-
4郭海霞,刘刚,帅海林,靖亚莎.三种方法治疗瘢痕疙瘩的临床疗效观察[J].中国美容医学,2009,18(1):76-77. 被引量:7
-
5任丽虹,肖志波,杨大平,滕雯,刘莺.五倍子对裸鼠瘢痕疙瘩动物模型的作用[J].中国美容医学,2009,18(6):806-808. 被引量:3
-
6胡亚兰,胡亚欣,郑永波,王薇薇,张伟玲.药物联合硅胶膜治疗瘢痕疙瘩疗效观察[J].医学理论与实践,2009,22(6):678-679. 被引量:6
-
7马静,刘流,李晓江,隋军.头颈部瘢痕疙瘩的综合治疗[J].中国耳鼻咽喉头颈外科,2009,16(6):305-307. 被引量:1
-
8戴儒奇,游文建,李诗运,肖欢.自制^(32)P敷贴器治疗瘢痕疙瘩[J].中国组织工程研究与临床康复,2009,13(28):5597-5600. 被引量:3
-
9鲁晓红,张荣荣,洪新月.瘢痕贴与弹力绷带联合治疗烧伤后瘢痕增生[J].中国美容医学,2009,18(11):1680-1680. 被引量:4
-
10文虹杰,刘流.瘢痕疙瘩的治疗研究进展[J].皮肤病与性病,2009,31(4):27-30. 被引量:1
二级引证文献223
-
1陈慧燕,田素科,赖色玉,庄建发,洪和泉.167例女性耳廓瘢痕疙瘩术后电子线放疗的疗效观察和预后影响因素分析[J].黑龙江中医药,2023,52(1):144-146.
-
2张玲,袁涵,徐江.剥蛋壳法切除联合曲安奈德注射治疗耳廓瘢痕疙瘩的疗效观察[J].兵团医学,2023(1):33-35. 被引量:1
-
3郭小伟.瘢痕疙瘩治疗方法的研究进展[J].医学信息,2017,30(26):19-21.
-
4黄振,冉国文,韩芳.硅酮霜与弹力套合用治疗烧伤后增生性瘢痕的疗效评价[J].医学信息(医学与计算机应用),2014,0(4):356-356. 被引量:1
-
5戴儒奇,游文建,李诗运,肖欢.自制^(32)P敷贴器治疗瘢痕疙瘩[J].中国组织工程研究与临床康复,2009,13(28):5597-5600. 被引量:3
-
6高明月,李敬满,彭晓燕.冷冻联合新的肤治疗儿童增生性瘢痕56例临床观察[J].中国美容医学,2009,18(10):1493-1494. 被引量:2
-
7鲁晓红,张荣荣,洪新月.瘢痕贴与弹力绷带联合治疗烧伤后瘢痕增生[J].中国美容医学,2009,18(11):1680-1680. 被引量:4
-
8高明月,张文显,蔺洁,郎琢琳,李敬满,彭晓燕,赵燕.冷冻联合瘢痕内注射治疗儿童增生性瘢痕疗效观察[J].中国美容医学,2010,19(3):371-371. 被引量:2
-
9蒋琪霞,胡素琴,周昕,彭青,何旭,徐敏.弥漫性血管内凝血继发41处全层伤口患儿的分阶段干预[J].中华护理杂志,2010,45(8):690-693. 被引量:5
-
10钟征明.瘢痕疙瘩治疗状态综述[J].中国医药指南,2010,8(26):35-37. 被引量:9
-
1唐悦玲,李小静.病理性瘢痕与炎性反应[J].中华整形外科杂志,2014,30(1):76-78. 被引量:4
-
2牛扶幼,康深松,陈言汤,刘林嶓.异搏定治疗增生性瘢痕20例[J].郑州大学学报(医学版),2002,37(2):244-244. 被引量:1
-
3张丽萍,孙玉敏,陈晓玲.结缔组织生长因子在纤维增生性疾病形成中的作用[J].医学综述,2007,13(20):1546-1548. 被引量:1
-
4王在岩,张平.白藜芦醇在纤维增生性疾病中的作用机制研究进展[J].医学研究杂志,2010,39(5):112-114. 被引量:1
-
5覃辉,韦金儒.单核细胞及其细胞因子与冠心病的关系[J].中国医学文摘(内科学),2006,27(3):204-207.
-
6曹广信,王维精,王少华.CTGF与病理性瘢痕关系研究进展[J].中国美容医学,2006,15(10):1211-1213. 被引量:7
-
7刘畅,陈敏亮.瘢痕疙瘩发病的分子机制研究进展[J].中国美容医学,2013,22(14):1557-1560. 被引量:5
-
8靳荷,李霞.TGF-β在角膜瘢痕形成及无瘢痕愈合中的作用[J].眼科新进展,2014,34(11):1087-1090. 被引量:7
-
9杨崇志,胡大海,武红.PPARγ激动剂与纤维增生性疾病研究进展[J].中华损伤与修复杂志(电子版),2008,3(3):48-50.
-
10胡启翔,王慧英,王颖艳,王建军.复春散Ⅱ号与曲安奈德联合应用治疗瘢痕疙瘩[J].中国美容医学,2008,17(12):1806-1806. 被引量:1