骨折后脂肪栓塞综合征患者49例诊疗分析

Clinical study of 49 patients with fat embolization syndrome following fracture

目的探讨骨折后脂肪栓塞综合征患者的发病机制、诊断及不同治疗效果。方法回顾性调查分析脂肪栓塞综合征患者49例,分别分析不同治疗方式的疗效。结果可见高压氧治疗,高剂量激素冲击和机器通气有助于提高脂肪栓塞综合征的治愈(P<0.05)。结论骨折后脂肪栓塞综合征应及时采用综合治疗,高压氧治疗,高剂量激素冲击和机器通气有助于提高治愈率。

Objective To analyse the pathogenesis, diagnosis, and the therapeutic effect under different therapy in patients of fat embolization syndrome following fracture, Methods 49 patients of fat embolization syndrome following fracture were retrospective analyzed focusing on the therapeutic effect under different therapy. Results Hyperbaric oxygen, higher dose of steroid and mechanical ventilation were found helpful to improve the therapeutic effect in patients of fat embolization syndrome following fracture （ P 〈 0.05 ）, Conclusion Patients of fat embolization syndrome following fracture should be treatmented timely with combined therapy, which comprises hyperbaric oxygen, higher dose of steroid and mechanical ventilation.