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强地松冲击治疗短暂性脑缺血发作的临床研究

Effect of High-dose Prednisone Pulse Therapy Treatment on Transient Ischemic Attack
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摘要 目的观察强地松冲击治疗短暂性脑缺血发作的疗效。方法30例患者均以强地松30mg/d,静脉滴注3~5d,冲击治疗结束后,予泼尼松60mg,1次/d,逐渐减量至停药。观察临床疗效。结果30例患者中显效21例,好转6例,无效或加重3例(死亡2例,无变化1例)。治疗总有效率达90%,不良反应发生率13.3%。结论大剂量强地松冲击疗法是治疗短暂性脑缺血发作安全、有效的方法。 Objective To investigate the clinical effect of high--dose methylprednisolone pulse therapy treatment on acute demyelinating encephalopathy. Methods All patients were treated with methylprednisolone 30rag every day,intervenous drop infusion three to five days, after the treatment, dehydrocortisone was given 60rag everyday, gradually extenuation until discontinuation, i and observed the clinical effect, l;esults Among 30 cases of therapeutic group, 21 cases showed effective, 6 cases were valid and 3 cases were inefficient (2 cases death, 1 cases no change). Cure rate and incidence of side effect were 90% and 13.3% respectively. Conclusion lligh-dose methylprednisolone pulse therapy is safe and effective in the treatment of acute demyelinating encephalopathy.
出处 《中外医疗》 2008年第11期9-10,共2页 China & Foreign Medical Treatment
关键词 强地松 短暂性脑缺血发作 冲击疗法 Prednisone Acute demyelinating encephalopathy Pulse therapy
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