代谢木糖产乙醇的酿酒酵母工程菌研究进展

Progress of Engineered Saccharomyces cerevisiae of Xylose Metabolism and Fermentation for Ethanol Production

随着能源价格的持续上涨,使用木质纤维素生产燃料乙醇已具有重要的实践意义。木糖是多数木质纤维素水解产物中含量仅次于葡萄糖的一种单糖,传统乙醇生产菌株酿酒酵母不能利用木糖,这为使用以木质纤维素为原料发酵生产乙醇带来了困难。多年以来人们试图通过基因工程和细胞融合等方法对其进行改造使其能够代谢木糖生产乙醇。本文主要介绍这方面的研究进展。

With the constant rise of energy price, it has a great practical meaning of using lignocellulose to produce ethanol. Xylose is a kind of monosaccharide whose content is only less than glucose in most lignocellulosic hydrolysates. There is some difficulty of producing ethanol from lignocellulose by the traditional ethanol production strain Saccharomyces cerevisiae, because it cannot metabolize xylose. People have tried to use genetic engineering technology and cell fusion method to modify Saccharomyces cerevisiae to make it metabolize xylose and produce ethanol for many years. This review indroduced the progress in this field.