周围动脉闭塞性疾病患者认知功能的调查

A survey on cognitive function of the patients with peripheral arterial occlusive disease

目的:探讨周围动脉闭塞性疾病与认知功能的关系。方法:对北京万寿路地区1730例60岁以上老年人进行电话访问、神经系统查体认知功能问卷及多普勒检查,对其中患有周围动脉闭塞性疾病人群的认知功能与非患病人群进行比较。结果:周围动脉闭塞人群的简易智能状态检查(MMSE)得分低于正常人群,其中计算力、延迟记忆及画钟测试两组得分差异有显著性。影响MMSE得分的因素包括年龄、文化程度、糖尿病、脑卒中史、肱踝动脉压力指数阳性、血浆纤维蛋白原水平。结论:周围动脉闭塞性疾病影响认知功能,可作为认知功能下降的预示指标。

Objective To investigate the relation between peripheral arterial occlusive disease （PAOD）and cognitive function in a community population, Methods 1 730 elders over 60 were investigated by phone call, survey questionnaire, physical examination, and Doppler detection. A comparison was made between the cognitive function of the elders with PAOD with that of those without PAOD. Results Scores of MMSE were lower in PAOD group than health group and there were significant differences between the two groups in ability of calculation, prolonged recall, and clock drawing test （P 〈 0,05）, The factors associated with MMSE scoring included age, educational level, diabetes, history of stroke, positive AAI, and plasma fibrinogen levels. Conclusion PAOD affects cognitive function and it can be used as a predictor for cognitive impairment.