摘要
目的探讨胆道外科感染的病原菌种类与分布及其对抗菌药物的敏感性,为临床合理使用抗菌药物提供依据。方法将2004年1月至2007年8月胆总管结石患者,术中抽取的胆汁标本送细菌培养阳性的133例160株需氧菌及其药敏试验结果作统计分析。结果 160株细菌中革兰氏阴性菌(G^-)112株(70.0%),革兰氏阳性细菌(G^+)48株(30.0%)。排列前五位的细菌依次为大肠埃希菌(43.8%)、粪肠球菌(14.4%)、肺炎克雷伯菌属(10.6%)、链球菌属(8.8%)和铜绿假单孢菌(5.6%)。对胆道细菌敏感的抗菌药物有亚胺培南、万古霉素、氨基糖甙类、青霉素类+β内酰胺酶抑制剂及第三、四代头孢菌素类。结论胆道感染病原菌的种类与分布及其对抗菌药物的敏感性存在地区和个体差异,根据当地药敏试验结果合理应用抗菌药物是控制胆道外科感染的关键。
Objective To explore type of biliary bacteria and their sensitivity to antibiotics. Methods The data of 133 patients with chololithiasis and 160 rinds of bacteria and their sensitivity to antibiotics were analyzed from 2004 to 2007. Results Gramnegative bacteria accounted for 112 （70. 0% ）. Gram positive bacteria accounted for 48 （30.0%）. The leading five bacteria detected were escherichia （43.8%）. Enterococcus（ 14.4% ） , Klebsiella（ 10.6% ） ,Streptococcus （8.8%） pseudomonas aeruginosa（5.6% ）. The bacteria were highly sensitive to imipenem,Vancomycin and amikacin,3^rd or 4^th generation of cephalosporins. Conclusion Types of biliary bacteria and their antibiotie sensitivity were changing. It is the key to cure biliary tract infection that using antibiotics properly according to microbial sensitivity tests.
出处
《临床急诊杂志》
CAS
2008年第2期92-94,共3页
Journal of Clinical Emergency
关键词
胆总管结石
胆汁
细菌培养
药敏试验
Chololithiasis
Bile
Bacteria culture microbial
Sensitivity tests
