我院精神药物在门诊处方中的应用分析

Analysis of Outpatient Prescriptions of the Psychotropic Drugs

目的:分析北京大学第一医院门诊处方精神药物的使用情况,为临床合理用药提供参考。方法:抽取2006年1月北京大学第一医院含有精神药物的门诊处方,对精神药物的用药品种、用药频度、药物间相互作用等进行统计分析。结果:在2810张精神药物门诊处方中,精神药物联合使用占77·3%;其中苯二氮类药处方数占到精神药物总处方的75·5%。精神障碍多合并高血压、糖尿病及冠心病。47张处方中有潜在的药物相互作用。结论:为避免发生药物间相互作用,对伴有慢性基础疾病的患者,精神药物安全、合理的使用须引起临床重视。

OBJECTIVE： To investigate the outpaitent use of psychotropic drugs in The First Hospital of Peking University for references of rational drug use. METHODS： The outpatient prescriptions of psychotropic drugs in Jan. 2006 in The First Hospital of Peking University were randomly collected for a statistical analysis in respect of the variety, DDDs and drug interactions of psychotropic drugs. RESULTS： Of the total 2,180 prescriptions reviewed, the rate of combined use of psychotropic drugs was 77.3 %, and 75.5 % involved use of Benzodiazepines. Mental disorders were more likely complicated with primary diseases such as hypertension, diabetes mellitus and coronary heart disease etc, and 47 were found to have potential drug interaction. CONCLUSION： Safe and rational use of psychotropic drugs should be emphasized for patients who have chronic basic diseases so as to avoid the occurrence of drug interaction.