含呋喃唑酮疗法根治幽门螺杆菌感染疗效观察

Furazolidone-included Therapy in Eradication of Helicobacter Pylori:Observation of Curative Effects

目的:观察含呋喃唑酮疗法对幽门螺杆菌的根治效果。方法:182例幽门螺杆菌患者,随机分为A组64例,B组61例,C组57例。A组采用雷贝拉唑、阿莫西林、呋喃唑酮;B组采用雷贝拉唑、阿莫西林、克拉霉素;C组雷贝拉唑、枸椽酸铋钾、呋喃唑酮、阿莫西林。疗程为1周,停药后1个月观察幽门螺杆菌根治情况。结果:A组幽门螺杆菌清除率为90.62%,B组幽门螺杆菌清除率为91.80%,C组幽门螺杆菌清除率为92.98%。3组比较无显著性差异(P>0.05)。结论:含呋喃唑酮疗法能有效根除幽门螺杆菌,且价格低廉。

OBJECTIVE ： To observe the effects of furazolidone - included therapy in eradication of Helicobacter pylori. METHODS： 182 patients with helicobacter pylori were randomly divided into three groups： 64 cases in group A were treated with rabeprazole ＋ arnoxicillin ＋ furazolidone; 61 cases in group B with rabeprazole ＋ amoxicillin ＋ clarithromycin; 57 cases in group C with rabeprazole ＋ bismuth potassium citrate ＋ amoxicillin ＋ furazolidone. The course of treatment was 1 week for three groups. One month after treatment, the eradication rate of helicobacter pylori in 3 groups were evaluated. RESULTS： The eradication rates of helicobacter pylori in A, B and C groups were 90.62%, 91.80% and 92.98%, respectively, showing no significant differences among the three groups （ P 〉 0.05）. CONCLUSION： The furazolidone - included therapy is cheap while effective in helicobacter pylori eradication.