进展期胃癌患者术中低渗热灌注化疗护理对策

Countermeasures of nursing in advanced gastric cancer by Intraoperative intraperitoneal hypotonic thermoperfusion chemotherapy

目的研究进展期胃癌患者术中腹腔低渗热灌注化疗护理对策。方法将施行胃癌根治术88例进展期胃癌患者随机分为低渗热化疗组30例，等渗热化疗组31例，对照组27例。观察三组患者的手术疗效、并发症和护理干预的变化。结果手术并发症发生率三组患者间的差异无显著性意义（P〉0．05）；5年生存率低渗热化疗组64％，等渗热化疗组59％，显著高于对照组32％；低渗热化疗组、等渗热化疗组和对照组复发时间分别为（24．6±9．7）个月、（15．6±8．7）个月和（10．2±5．2）个月；患者接受心理护理、术中护理、术后护理和不良反应及并发症的护理。结论护理干预对患者的恢复有一定的效果。

Objective To investigate the effectiveness and nursing of intra- operative intraperitoneal hyoptonic thermo perfusion chemotherapy （HTC） for advanced gastric cancer（AGC）.Methods 88 patients with advanced gastric cancer were randomly assigned into 3 groups： HTC group（n=30） received intreaperitoneal perfusion with heated hypotonic cisplatin solution immediately after radicalgastrectomy; isotonic thermoperfusion chemotherapy group（ITC, n=31）received intraperitoneal perfusion with heated isotonic cisplatin solution immediately after radical gastrectomy and the control group（n=27）,Observation of the three groups of patients with surgical treatment, complications and nursing intervention changes .Results The incidence of complications among the three groups with no significant differences statistically significant （P〉0.05） and the 5-year survival rate of low permeability of chemotherapy group 64% of the chemotherapy group isotonic 59%, significantly higher than 32%;permeability of chemotherapy group, isotonic heat chemotherapy group and the control group were recurrence time（24.6±9.7）months（15.6±8.7）months and （10. 2 ± 5.2） months, respectively;patients receiving psychological care, for the care of after-care and adverse reactions and complications of care. Conclusion Nursing intervention on the recovery of patients with a certain effect.