期刊文献+

Apelin与心房纤颤 被引量:2

Apelin and Atrial Fibrillation
下载PDF
导出
摘要 Apelin是一种较新的心血管活性调节物质,具有扩血管、降血压、提高心肌收缩力等效应,心房纤颤是临床上十分常见的心律失常,有关Apelin与心房纤颤关系的报道较少。现就Apelin与心房纤颤的关系研究进行综述,探讨Apelin在心房纤颤患者中的作用机制。 Apelin is a new peptide with cardiovascular activity, which may relax vessels, decrease blood pressure, and increase cardiac contractility. Atrial fibrillation is one of the most common arrhythmia. There is few report about the relation between Apelin and atrial fibrillation. This article reviewed the relationship between Apelin and atrial fibrillation as well as its mechanism.
出处 《医学综述》 2008年第9期F0002-F0002,1386,共2页 Medical Recapitulate
关键词 APELIN 心房纤颤 结构重构 Apelin Atrial fibrillation Structural remolding
  • 相关文献

参考文献19

  • 1Prystowsky EN,Benson DW Jr,Fuster V,et al. Management of patients with atrial fibrillation : a statement for healtheare professionals from the subcommittee on electrocardiography and eleetrophysiology, American Heart Association [ J ]. Circulation, 1996,93 ( 6 ) : 1262-1277.
  • 2O'Dowd BF,Heiber M,Chan A,et al. A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11 [ J ]. Gene, 1993,136 (1-2) :355-360.
  • 3Tatemoto K, Hosoya M, Habata Y, et al. Isolation and chaxacterization of a novel endogenous peptlde ligand for the human APJ receptor[ J]. Biochem Biophys Res Commun ,1998,251 (2) :471-476.
  • 4Hashimoto T, Kihara M, Ishida J, et al. Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells [ J ]. Arterioscler Thromb Vasc Biol,2006,26 (6) : 1267-1272.
  • 5Tatemoto K,Takayama K, Zou MX, et al. The novel pepfide apelin lowers blood pressure via a nitric oxide-dependent mechanism [ J ]. Regul Pept,2001,99 (2/3) :87-92.
  • 6Zhong JC,Yu XY, Huang Y, et al. Apelin modulates aortic vascular tone via endothelial nitric oxide synthase phosphorylafion pathway in diabetic mice [ J ]. Cardiovasc Res,2007,74 (3) :388-395.
  • 7Seyedabadi M, Goedehild AK,Pilowsky PM. Site-specific effects 'of apelin-13 in the rat medulla oblongata on arterial pressure and respiratlon [ J ]. Auton N eurosci, 2002,101 ( 1/2 ) : 32 -38.
  • 8Berry MF,Pirolli TJ,Jayasankar V,et al. Apelin has in vivo inotropic effects on normal and failing hearts [ J ]. Circulation, 2004, 110 ( 11 Suppl 1 ) : 187-193.
  • 9Farkasfalvi K,Stagg MA ,Coppen SR,et al. Direct effects of apelin on cardiomyecyte contractility and electrophysiology [ J ]. Biechem Biophys Res Commun ,2007,357 (4) :889-895.
  • 10Szokodi I, TaviP, FoldesG, et al. Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility[ J ]. Circ Res,2002,91 (5) :434-440.

二级参考文献19

  • 1Wang W,J Biol Chem,2000年,275卷,22期,16899页
  • 2Linz W,J Hypertens,1993年,11卷,Suppl 5期,S96页
  • 3Moore J P,Kitchen S G,Pugach P,Zack A.The CCR5 and CXCR4 coreceptors-central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection[J].AIDS Res Hum Retrovir,2004,20(1):111-26.
  • 4Reaux A,De M N,Skultetyova I,et al.Physiological role of a novel neuropeptide,apelin,and its receptor in the rat brain[J].J Neurochem,2001,77(4):1085-96.
  • 5Taheri S,Murphy K,Cohen M,et al.The effects of centrally administered apelin-13 on food intake,water intake and pituitary hormone release in rats[J].Biochem Biophys Res Commun,2002,291(5):1208-12.
  • 6Katugampola S D,Maguire J J,Matthewson S R,Davenport A P.[^(125)I]-[Pyr(1)] Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man[J].Br J Pharmacol,2001,132(6):1255-60.
  • 7Ishida J,Hashimoto T,Hashimoto Y,et al.Regulatory roles for APJ,a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo[J].J Biol Chem,2004,279(25):26274-9.
  • 8Tatemoto K,Takayama K,Zou M X,et al.The novel peptide apelin lowers blood pressure via a nitric oxide-dependent mechanism[J].Regul Pept,2001,99(2-3):87-92.
  • 9Szokodi I,Tavi P,Foldes G,et al.Apelin,the novel endogenous ligand of the orphan receptor APJ,regulates cardiac contractility[J].Circ Res,2002,91(5):434-40.
  • 10Gábor F,Ferenc H,István S,et al.Circulating and cardiac levels of apelin,the novel ligand of the orphan receptor APJ,in patients with heart failure[J].Biochem Biophys Res Commun,2003,308(3):480-5.

共引文献52

同被引文献8

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部