胰性脑病个性化综合治疗的临床分析

Clinical Analysis of Personality and Combination Treatment in Pancreatic Encephalopathy

目的:探讨急性重症胰腺炎(SAP)并发胰性脑病(PE)的临床特点、诊断治疗方法及采用个性化综合治疗的意义。方法:将湘雅医院2000年1月至2006年12月间诊治的19例PE患者临床资料进行分类,采用个性化综合治疗,并对其结果进行分析。结果:19例PE中经采用个性化综合治疗,成活11例,死亡8例,死亡率为42.1%。结论:胰性脑病根据病情抑制胰酶释放、选择适当的个性化综合性治疗方法处理,不但提高了急性胰腺炎的治愈率,而且提高了胰性脑病的疗效。

Objectives： To investigate the clinical characteristics, diagnosis and treatment of severe acute pancreatitis （SAP） complicating pancreatic encephalopathy （PE）, and to evaluate the significance of the personality treatment and combination treatment. Methods： 19 PE cases, treated in Xiangya hospital from January 2000 to December 2006, were selected. Their clinical data were classified, according to which,the patients were treated with personality and comprehension method.The results of treatment were analyzed. Results： Among the 19 PE patients, 11 cases survived, 8 cases died, the death rate was 42.1%. Conclusion： Inhibiting the release of pamcreatin and choosing the right treatment based on severity of PE can elevate the cure rates of SAP as well as the therapeutic effects of PE.