牙﹑微型种植体支抗联合支抗牵张成骨治疗齿槽突裂的动物实验研究

Distraction Osteogenesis for Repair of Alveolar Cleft by Tooth and Micro-Implant Anchorage-Borne Intraoral Distractor : an Experimental Study

目的:建立牙、微型种植体支抗联合支抗牵张成骨治疗齿槽突裂的动物模型,评估其治疗效果。方法:成年杂种犬实验组6只,对照组2只。首先形成齿槽突裂外科模型,2周后手术截骨形成一含牙的骨运送盘,在骨运送盘上植入微型种植体支抗,一周后开始牵引。牵张完成后1,2,3月各处死动物2只,对照组术后1月处死。取标本作大体,放射学,及组织学检查。结果:齿槽突裂隙完全关闭,牵张区为丰富的新骨。结论:牙、微型种植体支抗联合支抗牵张成骨能够很好的关闭犬的齿槽突裂隙。

Objective：To establish an animal model for repair of alveolar cleft with distraction osteogen- esis by tooth and MIA-borne intraoral distractor. Methods-Eight adult mongrel dogs were divided into two groups： the control （n=2） and the experimental groups. Alveolar bone resection was made surgically at first. After 2 weeks, the tooth-bone complex transport disc was formed by osteotomy, and MIA was implanted into it. The gradual distraction was started After 1 week latency. The dogs were killed at 1 month, 2 months, 3 months after completion of distraction （1 month in control group）. The samples were evaluated by clinical examination, x-ray, histology observation. Result：The alveolar bone resection had disappeared, and the distraction zone had formed new bone. Conclusion：Alveolar cleft can be repaired and achieved functional reconstraction under DO by tooth and MIA-borne intraoral distractor.