脑电熵在麻醉深度监测中的意义

Role of entropy in monitoring anesthetic depth

随着肌松药和镇痛药等药物的联合应用，现代全身麻醉的深度、患者的意识状态常常被掩盖或难以判断。以往的传统体征（血压、心率、呼吸和瞳孔等）已不能准确地反映麻醉深度。目前，有关研究重点集中在脑电活动方面，如脑电双频指数（bispectral index，BIS）、脑电熵（entropy）、听觉诱发电位等。现就entropy在麻醉深度监测中的意义及其研究进展作一综述，并与脑电双频指数进行比较。

Depth of anesthesia and patients＇consciousness status often be covered or become difficult to judge because of combining usage of muscle relaxants and analgetic agents. Anesthetic depth can not be exactly reflected just only by traditional vital signs such as blood pressure, heart rate, respiration status, pupil size. Recent studies of anesthetic depth monitoring are focused on cerebral electronic activity such as bispectral index （BIS） of electroencephalogram, entropy, auditory evoked potentials （AEP）. This article is to review the value of entropy on monitoring depth of anesthesia with comparison to BIS and outline the recent advance in entropy research.