苦黄口服液质量标准研究

Study on Quality Standard of Kuhuang Oral Liquid

目的:建立苦黄口服液的质量标准。方法:采用薄层色谱法鉴别苦黄口服液中大黄、茵陈、大青叶等药材;采用高效液相色谱法测定制剂中大黄酚的含量。结果:薄层斑点清晰,重现性好;含量测定大黄酚平均回收率为98.3%,RSD=1.6%。结论:方法简便、准确,可供苦黄口服液的质量控制。

Objective： To establish the quality control standard of KuHuang Oral Liquid. Methods： Radix et Rhizoma Rhei, Herba Artemisiae Scopariae and Fructus Jujubae were indentified by TLC, and the content of Chrysophanol was determined by HPLC. Results： The TLC sports developed were fairly clear, and the blank test showed no interference. The average recovery was 98.3% , RSD was 1.6%. Conclusion： The method is simple and reliable. It can be used in quality control of KuHuang Oral Liquid.