平喘降气汤治疗支气管哮喘急性发作的临床研究

Clinic Study of Pingchuan JiangQi Tang in Treating Asthra Attack

目的:探讨平喘降气汤治疗支气管哮喘急性发作临床疗效。方法:把符合入选条件的130例病人随机分成治疗组和对照组各65例,治疗组予以平喘降气汤100mL,1天2次口服;对照组予以博利康尼片2.5mg,1天3次口服,两组均以3周为1个疗程,疗程结束后,观察疗效、EOS、IgE、FEV1、PEFR等指标变化。结果:(1)治疗组临床疗效有效率为90.77%,对照组有效率为87.69%,两组间临床疗效无显著性差异(P>0.05)。(2)治疗组降低血EOS、IgE均明显优于对照组(P<0.05),治疗组与对照组在改善肺功能指标FEV1、PEFR方面无显著性差异(P>0.05)。结论:平喘降气汤治疗支气管哮喘急性发作有较好的临床疗效,显著改善患者肺功能的同时,又能减轻患者气道的炎性反应。

Objective： To assess the efficacy of Pinchuan JianQi Tang in treating asthma attack. Methods： 130 patients with asthma were randomly divided into treating and control groups. There were 65 cases in each group. In treating group, 100mL Pinchuan JianQi Tang liquids were given to each patient each time twice a day. In control group, 2.5mg of Bricanyl tablet was given three times a day. The treatment course was three weeks. Blood level of EOS,IgE and FEV1, PEFR were respectively tested before and after treating. Results ： （ 1 ）The efficacy in treating group is 90.77%, in control group is 87.69% , there is no obvious difference between the treating and control groups. The treating group can decrease the plasma level of EOS, IgE, however, The control group have no effect on it . Both group have the same effect on improving the FEV1 ,PEFR. Conclusion： Pinchuan JianQi Tang is effective on asthma attack, and it can relieve the inflamation in the air way.