摘要
蛋白质组学是系统研究细胞或组织全套蛋白质生物学信息的科学，其中尿液蛋白质组学以其独特的优点广泛应用于基础和临床研究领域。糖尿病肾病是糖尿病最常见且危害巨大的并发症之一，许多学者运用尿液蛋白质组学分析方法对糖尿病肾病进行研究，发现了一些与糖尿病肾病相关的生物学标志及可能的发生机制，展示了尿液蛋白质组学技术在糖尿病肾病早期诊断、动态监测病情及发现新的治疗靶点方面的前景。
Proteomics is to study the entire protein expression of a biological system. Urinary proteomics is applied generally in the field of basic and applied research for its distinct advantage. Diabetic nephropathy （DN） is a common complication with enormous hazard in diabetes mellitus. Recently, urinary proteomics has been applied to the study of DN, and has identified new mechanisms and potential urinary markers of DN. Urinary proteomics has potential application prospects in early diagnosis, monitoring pathogenic condition dynamically and the discovery of new targets to treatment.
出处
《国际内分泌代谢杂志》
2008年第3期189-191,共3页
International Journal of Endocrinology and Metabolism
基金
国家自然科学基金资助项目（30670980）
