基底动脉尖综合征临床特点及预后分析

Clinical characteristic and prognosis of patients with top of the basilar syndrome

目的分析150例基底动脉尖综合征临床特点及30d预后,探讨其临床特点及预后不良的相关因素。方法跟踪随访150例诊断明确患者发病时临床表现,死亡患者死亡原因,并于入院时及病后30d分别进行NIHSS、改良Rankin残障量表(MRS)评分,分析患者30d预后,及分析预后不良的相关因素。结果本组150例基底动脉尖综合征30d病死率为10%,眩晕及偏瘫为主要首发症状,脑疝及合并症为主要死亡及高残障的主要原因。病变部位(OR=0.112,P=0.002)、病变个数(OR=0.460,P=0.030)、并发症(OR=0.344,P=0.001)与预后不良相关。结论基底动脉尖综合征及早诊断、积极治疗大部分预后良好,关键在疾病预防。

Objective To investigate the clincical characteristic and 30 days outcome of patients with top of the basilar syndrome and to discuss their correlated factors. Methods One hundred and fifty patients with top of the basilar syndrome were followed up. The clinical symptom and the causation of death were observed, NIHSS and MRS score were made from the bagining to the 30th day of disease. The correlated factors with poor outcome were analyzed. Results The mortality of the 150 patients with top of the basilar syndrome during 30 days was 10%, giddiness and hemiplegy were the primary symptom, herniation and complications were the main reasons of death and poor physical the disabilities. The damaged position （OR=0.112, P=0.002）, and the damaged number （0R=0.460, P=0.030） and the complications （OR= 0.344, P=0.001） were related with the poor prognosis. Conclusions Early diagnosis, and active treatment can gain good prognosis. Prevention is the most important.