中药治疗早期甲状腺相关眼病的临床观察

Clinical observation on TCM treatment of the earlier period Thyroid—associated ophthalmopathy

目的观察中药治疗早期甲状腺相关性眼病（TAO）的疗效。方法回顾总结本院2004～2006年门诊25例（38只眼）早期甲状腺相关性眼病病例资料。所有病人均用单纯中药治疗，选用燥湿化痰、行气开瘀散结和清热解毒、通络祛瘀的药方。结果活动期15只患眼平均CAS值治疗1个月后减小显著（P〈0.05）；3个月后有效率为93％，显效率为93％。28只上睑退缩患眼治疗2个月后平均值减小显著（P〈0．05）；3个月后有效率为89％，显效率为43％。25只上睑迟落患眼治疗2个月后平均值减小显著（P〈0．05）；3个月后有效率88％，显效率为44％。12只突眼患眼治疗3月后平均值减小显著（P〈0．05），有效率达83％，显效率为50％。结论对于不能使用类固醇类及其他免疫抑制剂的早期TAO病人，可采用中药和支持疗法，以有效控制早期症状减少并发症发生。中药疗法为早期TAO患者的治疗提供了更多选择。

OBJECTIVE To observe the clinical effect of Chinese medicine on the earher period of Thyroid - associated ophthalmopathy （TAO）.METHODS Data of 25 patients （38 eyes） with earlier period of TAO collected from 2004 to 2006 were retrospectively analyzed. All patients were treated with Chinese herbs under the principle of Zaoshi Huatan（燥湿化痰）,Xingcli Huayu Sanjie（行气开瘀散结）and Qingre Jiedu（清热解毒）,Tongluo Queyu（通络祛瘀）. RESULTS After a month of treatment, 15 eyes in activities of the average value of CAS decreased significandy （ P 〈 0.05） ; Three months later the effective rate was 93 %, significant efficiency was 93 % .Two months after treatment, 28 eyes with upper eyelid retraction the average decrease was significant （ P 〈 0.05）;Three months later the effective rate was 89 %, and the significant efficiency was 4 3 %. Twenty - five eyes with eyelid later which average reduction was significant（ P 〈 0.05）after 2 month; Three months later the effective rate was 88 % ,and efficiency was 44 %. Twelve eyes of exophthalmos after three month of treatment, the average decrease was significant（ P 〈0.05） ,efficient rate was 83 %, significant efficiency was 50 %. CONCLUSlONS The early phase TAO patients who can not use steroids and immunosuppressants , with Chinese herbs and some support therapy, the early symptoms can be effectively controlled and can reduce complications. Chinese medicine therapy provides other choices for the treatment of patients with early TAO.