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抗HIV感染新药:Raltegravir 被引量:1

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出处 《疑难病杂志》 CAS 2008年第5期304-304,共1页 Chinese Journal of Difficult and Complicated Cases
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参考文献4

  • 1Iwamoto M, Wenning LA, Petry AS, et al. Safety, tolerability, and pharmacokinetics of raltegravir after single and multiple doses in healthy subjects [J]. Clin Pharmacol Ther,2007,21 (8) :22-24.
  • 2Kassahun K, McIntosh I, Cui D, et al. Metabolism and disposition in humans of raltegravlr (MK-0518),an anti-AIDS drug targeting the human immunodeficiency virus 1 integrase enzyme[J]. Drug Metab Dispos,2007, 35(9) :1 657-1 663.
  • 3Grinsztejn B, Nguyen BY, Katlama C, et al. Safety and efficacy of the HIV- 1 integrase inhibitor resistant virus: a phase Ⅱ randomised controlled trial [J]. Lancet,2007,369(9 569) : 1 261-1 269.
  • 4Markowltz M, Nguyen BY, Gotuzzo N. Rapid and Durable Antiretroviral Effect of the HIV-1 Integrase Inhibitor Raltegravir as Part of Combination Therapy in Treatment-Naive Patients With HIV-1 Infection: Results of a 48-Week Controlled Study [ J ]. J Acquir Immune Defic Syndr, 2007,46 (2) : 125-133.

同被引文献10

  • 1Zhan P, Liu X. Designed multiple ligands : an emerging anti-- HIV drug discovery paradigm. Current Pharmaceutical Design, 2009, 35 (15) : 1893- 1917.
  • 2Zhan P, Li Z, Liu X. Sulfanyltriazole/tetrazoles: A Promising Class of HIV-- 1 NNRTIs. Mini-Rev Med Chem, 2009,9 (8) : 1014-1023.
  • 3Erik De Clercq. Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV. International Journal of Antimicrobial Agents, 2009,33 : 307- 320.
  • 4Lieberman Blum SS, Fung HB, Bandres JC. Maraviroc: a CCRs-receptor antagonist for the treatment of HIV- 1 infection. Clinical Therapeutics, 2008,30 : 1228 - 1250.
  • 5Cocohoba J,Dong BJ. Raltegravir: The First HIV Integrase Inhibitor. Clinical Therapeutics,2008,30(10) : 1747-1765.
  • 6Iwamoto M, Wenning LA, Pet ry AS, et al. Safety, tolerability, and pharmacokinetics of raltegravir after single and multiple doses in healthy subjects. Clin Pharmacol Ther,2007,21(8) :22-24.
  • 7Schiller DS,Youssef Bessler M. Etravirine:A second-Generation nonnucleoside reverse transcriptase inhibitor (NNRTI) active against NNRTI resistant strains of HIV. Clinical Therapeutics, 2009,31(4) :693-704.
  • 8A. Fayet,A. Beguin,B. Zanolari. A LC-tandem MS assay for the simultaneous measurement of new antiretroviral agents: Raltegravir,maraviroe, darunavir,and etravirine. Journal of Chromatography B,2009,877 : 1057- 1069.
  • 9王德克,蔺红伟,肖凯.Maraviroc和Raltegravir:两种新型的抗HIV药物[J].世界感染杂志,2008,8(5):382-384. 被引量:1
  • 10马培奇.2008年上半年全球首次批准新药[J].中国医药技术经济与管理,2008,2(12):20-28. 被引量:1

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