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33例局部晚期胰腺癌三维适形放疗同步卡培他滨化疗的临床观察 被引量：3

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摘要 胰腺癌是最常见的消化道恶性肿瘤之一，发病率呈逐年上升趋势，仅有10％～15％的病例可行手术切除。对局部晚期胰腺癌，放疗联合化疗已成为主要治疗手段。三维适形放疗技术因其能使肿瘤病灶接受高剂量，而周围正常组织却受量极低，在晚期胰腺癌的放疗中越来越多地被应用。笔者应用三维适形放疗（3DCRT）联合同步卡培他滨口服化疗治疗局部晚期胰腺癌，取得较好疗效，现报道如下。
作者 牟建国 赵海燕 陈强华 贾中耀 王淑霞 张传建
机构地区 山东省临沂市人民医院放疗科
出处 《中华放射肿瘤学杂志》 CSCD 北大核心 2008年第3期173-174,共2页 Chinese Journal of Radiation Oncology
关键词 局部晚期胰腺癌 三维适形放疗 放疗联合化疗 卡培他滨 临床观察 同步 消化道恶性肿瘤 适形放疗技术
分类号 R686 [医药卫生—骨科学]
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参考文献7

  • 1Wilkowski R, Thoma M, Weingandt H, et al. Chemoradiation for ductal pancreatic carcinoma: principles of combining chemotherapy with radiation, definition of target volume and radiation dose. J Pancreas,2005,6:216 - 230.
  • 2Cartwright TH, Cohn A, Varkey JA, et al. Phase H study of oral capecitabine in patients with advanced or metastatic pancreatic cancer. J Clin Oncol,2002,20:160 - 164.
  • 3Sawada N, Ishikawa T, Sekiguchi F, et al. X - ray irradiation induces thymidine phosphorylaseand enhances the efficacy of capecitabine(Xeloda) in human cancer xenografts. Clin Cancer Res, 1999,10:2948 - 2953.
  • 4李玉,闫英,田启和,郭占文.三维适形放射治疗加动脉化疗胰腺癌的疗效分析[J].中华放射肿瘤学杂志,2002,11(1):15-17. 被引量：28
  • 5Schneider BJ, Ben - Josef E, McGinn C J, et al. Capecitabine and radiation therapy preceded and followed by combination chemotherapy in advanced pancreatic cancer. Int J Radiat Oncol Biol Phys, 2005,63 : 1325 - 1330.
  • 6Dunst J, Reese T, Sutter T, et al. Phase I trial evaluating the concurrent combination of radiotherapy and capecitabine in rectal cancer. J Clin Oncol,2002,20:3983 -3991.
  • 7Saif MW, Eloubeidi MA,Russo S,et al. Phase I Study of capecitabine with concomitant radiotherapy for patients with locally advanced pancreatic cancer: expression analysis of genes related to outcome. J Clin Oncol,2005,23:8679 -8687.

二级参考文献4

共引文献27

同被引文献27

  • 1李梅,王芳,魏万里.肿瘤热疗的研究进展[J].现代肿瘤医学,2006,14(9):1169-1171. 被引量：20
  • 2Therasse P, Arbuck S, Eisenhauer EA, et al. New guidelines to evaluate the response to treatment in solid tumors [ J ]. National Cancer Institute,2000,92:205 - 216.
  • 3Wilkowski R, Thoma M, Weingandt H, et al. Chemoradiation for ductal pancreatic carcinoma: principles of combining chemotherapy with radiation, definition of target volume and radiation dose[ J]. J Pancreas,2005,6:216 - 230.
  • 4Sawada N, Ishikawa T, Sekiguehi F, et al. X-ray irradiation induces thymidine phosphorylase and enhances the efficacy of capecitabine ( Xeloda ) in human cancer xenografts [ J]. Clin Cancer Res, 1999, 5:2948 - 2953.
  • 5Cartwright TH, Cohn A, Varkey JA, et al. Phase study of oral eapecitabine in patients with advanced of metastatic pancreatic cancer [ J ]. J Clin Onco1,2003,20 : 160 - 164.
  • 6Burris HA, Moore M J, Anderson J, et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer:a randomized trial[ J]. J C lin Oncol, 1997,15 (6) :2403 - 2413.
  • 7Rotheberg ML, Moore MJ, Cripps MC, et al. A phase Ⅱ trial of gemcitabine in patients with 5-FU refractory pancreas cancer[ J]. Ann Oncol, 1996, 7:347 - 353.
  • 8Li CP, Chao Y, Chi KH, et al. Concurrent chemoradiotherapy treatment of locally advanced pancreas cancer:Gemcitabine versus 5-fluorouracil. A randomized controlled study [ J]. Int J Radiat Oncol Biol Phys, 2003,57 ( 1 ) :98 - 104.
  • 9Stahopoulos GP, Syrigos K, Polyzos A, et al. Front-line treat- ment of inoperable or metastatic pancreas cancer with gemcitabine and capecitabine : an intergroup, multicenter, Ⅱ phase study [ J ]. Ann Oncol,2004,15 ( 2 ) :224 - 229.
  • 10Herrmann R, Bodoky G, Ruhstaller T, et al. Gemcitabine plus capccitabinc compared with gemcitabine alone in advanced pancreatic cancer: a randomized, multicenter, Ⅲ phase trial of the Swiss Group for Clinical Cancer Research and the Central European Cooperative Oncology Group [J]. J Clin Oncol, 2007,25 (16) :2212 - 2217.

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中华放射肿瘤学杂志
2008年 第3期

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