期刊文献+

肛肠手术后奈福泮和曲马朵患者自控静脉镇痛效果比较 被引量:5

Comparison of PCIA effect of nefopam and tramadol on postanorectal operation pain
原文传递
导出
摘要 目的对比观察肛肠手术后奈福泮和曲马朵患者自控静脉镇痛的效果。方法ASAⅠ~Ⅱ级60例择期骶管阻滞下行肛肠手术的患者,随机分为N组(奈福泮组)30例、T组(曲马朵组)30例,骶管阻滞用药含0.5%罗哌卡因。手术结束时开启静脉自控镇痛泵,N组给奈福泮160 mg+格拉司琼3 mg,T组给曲马朵800mg+格拉司琼3 mg,均稀释至100 ml,背景量2 ml/h,自控剂量0.5 ml/次,锁定时间20 min。术后48h内应用疼痛视觉模拟评分(VAS)对两组患者进行镇痛效果评估,并记录不良反应。结果两组患者的术后疼痛明显减轻(VAS均<3),镇痛效果无统计学差异,N组患者的不良反应明显少于T组。结论奈福泮与曲马朵的肛肠术后镇痛效果相近,但前者不良反应明显少。 Objective To compare the patient controlled intravenous analgesic effect of nefopam and tramadol on postanorectal pain. Methods Sixty patients, ASA I-Ⅱ scheduled caudal block for anorectal surgery, were randomly divided into two groups : Group N ( nefopam group, nefopam 160 mg + gran-isetron 3 mg) 30 cases, group T ( tramadol group, tramadol 800 mg + granisetron 3 mg) 30 cases. 0.5% ropivacaine was used in caudal block. At the end of operation the background infusion of PCA pump was 2 ml/h, a bolus 0.5 ml with 20 minute lock-out. The pain relief of patients in 48 hours, using visual analogue scale (VAS) to assess the analgesic effect of the two groups, were compared. Results The VAS in group N and T patients were significantly reduce postoperatively ( VAS 〈 3 ), and the side effects in group N patients were significantly less than that in group T. Conclusion The analgesic effect of nafopam is similar to tramadol after anorectal operation, but with less side effects.
出处 《实用疼痛学杂志》 2008年第2期110-112,共3页 Pain Clinic Journal
关键词 奈福泮 曲马朵 中医肛肠手术 镇痛 患者控制 Nefopam Tramadol Anorectal,Surgery Analgesia, Patient-Controlled
  • 相关文献

参考文献6

  • 1[1]Souter AJ,Fredman B,White PF.Controversies in the perioperative use of nonsteroidal antiinflammatory drugs.Anesth Analg 1994;79 (6):1178-1190.
  • 2[2]Baird MB,Schug SA.Safety aspects of postoperative pain relief.Pain Digest 1996;6:219-25.
  • 3[3]Beilin B,Shavit Y,Trabekin E,et al.The effects of postoperative pain management on immune response to surgery.Anesth Analg,2003,97 (3):822-827.
  • 4[4]Dayer P,Collart L,Desmeules J.The pharmacology of tramadol.Drugs 1994,47 Suppl.1:3-7.
  • 5[5]张立生,刘小立主编.现代疼痛学.石家庄:河北科技出版社,1998,1384-1387.
  • 6[6]Australian Adverse Drug Reactions Bulletin.2003,22:2.

共引文献2

同被引文献29

引证文献5

二级引证文献53

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部