结核疹和分枝杆菌相关性研究进展

Relationship between tuberculid and Mycobacteria

皮肤结核疹与分枝杆菌相互关系一直存有争议。一般认为结核疹是对结核分枝杆菌或其代谢产物的一种超敏反应，结核分枝杆菌不会直接引起结核疹。近年来，有研究在结核疹皮损中培养出非结核分枝杆菌，且聚合酶链反应可检出结核分枝杆菌和非结核分枝杆菌。综述目前各类结核疹与分枝杆菌相关性的研究进展，为结核疹病因探索和有效治疗的研究提供参考。

The relationship between tubereulid and mycobacteria remains conflicting. It is generally considered that tubereulid is a hypersensitivity response to Mycobacterium tuberculosis or its metabolic products, but not directly caused by this pathogen. Recent studies have reported successful isolation of nontubereulous mycobacteria by culture as well as detection of tuberculous and nontubereulous mycobacteria by PCR from tuberculid lesions, This paper states the advances in researches related to tubereulid and mycobacteria, which may provide evidence for the investigation into the etiology and treatment of tuberculid.