四氮杂杯[2]芳烃[2]三嗪的合成及其叠氮化研究

Study on synthesis of tetraazacalix[2]arene[2]triazine and its azidotion

研究了四氮杂杯[2]芳烃[2]三嗪的合成及其叠氮化。以三聚氯氰和间苯二胺（摩尔比〉2：1）为原料，碳酸钾为缚酸剂，四氢呋喃为溶剂，在冰浴条件下合成中间体N，N’-二（4，6-二氯-1，3，5-均三嗪-2-基）-1，3-苯二胺，产率为85．8％；该中间体和间苯二胺（摩尔比为1：1）丙酮为溶剂，在室温条件下反应，生成四氮杂杯[2]芳烃[2]三嗪，产率为45．5％；四氮杂杯[2]芳烃[2]三嗪和叠氮钠在40-50℃条件下反应生成四氮杂杯[2]-1，5-芳烃[2]-2-叠氮基-1，3，5-三嗪产率为90．0％。产物通过元素分析、红外光谱和氢谱的表征，其结构得到了确定。

This paper studied the synthesis of tetraazacalix [ 2 ] arene [ 2 ] triazine and its azidotion. In ice temperature,using cyanuric chloride and m-phenylenediamine （the mole ratio 〉 2 ： 1 ） as materials, potassium carbonate was taken as neutralisatal reagents, THF as solvent, synthesized the intermediate, the yield may up to 85.8% ;synthesized tetraazacalix[2] arene[2 ] triazine by the intermediate and m-phenylenediamine （the mole ratio 1 ： 1 ） , in room temperature, acetone as solvent, the yield is 45.5% ;tetraazacalix[2] arene[ 2 ] triazine and its azidotion was prepared in 40 - 50 ℃ synthesized its azidotion by tetraazacalix [ 2 ] arene [ 2 ] triazine and sodium azide, the yield is 90.0%. The product was characterized by IR, element analysis and ^1H NMR and its structure was also determined.