C反应蛋白与冠状动脉分叉病变支架术中相关侧支受压关系探讨

Relationship between C-reactive protein and collateral compression in percutaneous coronary stent implantation

目的探讨C反应蛋白(CRP)与冠状动脉分叉病变支架术中相关侧支受压的关系。方法术前测定冠状动脉分叉病变,需冠状动脉支架治疗的123例患者的血浆CRP浓度。根据术中相关侧支受压程度分为明显受压组(n=42)和不明显受压组(n=81)。比较两组间血浆CRP浓度及侧支受压的相关性。结果侧支明显受压组较不明显受压组CRP增高(P<0.01),CRP浓度与侧支受压程度呈明显的正相关(r=0.507,P<0.001)。结论血浆CRP与冠状动脉分叉病变支架术中相关侧支受压有密切关系。

Objective To assess the correlation of serum C-reactive protein（CRP） with the coronary collateral compression in bifurcation lesions in percutaneous coronary stent implantation （ PCI ）, Methods 123 cases needed PCI were divided into two groups： collateral compression group （n = 42） and control group （n = 81）. The serum content of CRP was measured before PCI. Results The serum level of CRP was significantly higher in collateral compression group than control one, （ P 〈 0. 01 ）. The level of CRP was positively correlated with the percentage of collateral compression（ r = 0. 507 ,P 〈 0. 001 ）, Conclusion There is a close relationship between the serum level of CRP and the extent of collateral compression in percutaneous coronary stent implantation.