36例初发2型糖尿病诺和灵强化治疗的临床分析

Chinical Analysis of 36 cases Primary Type Ⅱ diabetic Treated with Novelin

目的：观察诺和灵强化治疗初发2型糖尿病的临床疗效。方法：69例2型糖尿病病人,随机分为2组,观察组36例：住院期间要求严格饮食控制、适当体育锻炼,同时均给予诺和灵30R三餐前、诺和灵N睡前皮下注射,血糖控制后改为诺和灵30R早晚二次,最少治疗3个月,最长坚持治疗6个月。然后根据血糖调整使用药物剂量。对照组33例：门诊治疗和随访,予以制定严格饮食控制、适当的体育锻炼计划；同时口服格列齐特,剂量根据血糖调整。每周门诊检测多点血糖、血压等1-2次。结果：观察组使用胰岛素血糖达标所用时间为（10±3）d,对照组为（21±7）d,经t检验（P〈0.05）,差异有显著性。结论：诺和灵强化治疗初发2型糖尿病,快速降糖,解除高血糖毒性作用,促使胰岛B细胞分泌曲线恢复,降低胰岛素抵抗。

Objective：To observe the effect of novolin on Primary trpe 2 diabetrc patients. Method：69 cases were dirded in to ohservaition grorp（36 cases） and. cantral growp （33 cases）, randomly. Ih observation growp. Novolin R. were injected three times befere dinner, subcutaneons injectror of Novolin N before sleep, in the mean while, diet cortral and proper exercise were adopbed. Afterg ly cermic were controlled. Novolin 30R was tiwece in the morning and evening, last for 1-2 to months. Then adjnstel the drtug dosage accoding to the glycermic. In the control growp： They were controlled diet, proper training exercise were under-went. with oral glielazide accordingto the glycemic. Examined the multipoint glycemic at clini, one week. Reswlt：There＇s sigmficant chfference （P〈0.05） betwaen observation growp （10±3） d. and control group （21±7） d. for the standard gly cemic level after llsing of in swlin. Conclusion ： It can redwce the poison action of hypergly cemia, to treat primary type 2 diabetic with novolin.