预防双“J”管上结石形成的研究

Study on the prevention of stone formation on the double J catheters

目的:探索双J管上结石形成的预防措施。方法:本研究选择上尿路手术患者60例,所有患者术中均放置同一规格的双J管。60例患者随机平均分为A、B两组,A组口服枸橼酸钾片2.0g,3次/d。B组为对照组,无特殊处理。两组患者均于术后6周拔管。大体观察两组患者双"J"管上结石形成情况,并用电子天平称重。结果:大体观察:A组患者双"J"管仅有9例可见管壁颜色改变,无肉眼可见的结石形成。B组28例双"J"管有明显的沉积物,使管壁粗糙、颜色改变,其中11例双"J"管管壁及管腔内出现肉眼可见结石颗粒附着。称重:A组平均重为(0.8105±0.1876)g,B组(1.3159±0.2311)g,P<0.05。结论:枸橼酸钾能有效预防双"J"管结石的形成,并且安全、不良反应少。

Objective To explore the measures to prevent stone formation on the double J catheters. Method Sixty cases with upper urinary tract stone were implanted with double J catheters （F6） during operation. These 60 cases were randomly divided into group A and B, with 30 members in each group. Group A took potassium citrate pills （2.0g, 3 times per day）. There was no special treatment to group B （the contrastive group）. All the catheters were pulled out 6 weeks after operation under cystoscope. Stone formation on the double J catheters of the cases were examined by gross and weighted. Results Only 9 eases of group A showed color change in their catheters and there was no stone seen with bare eyes. Twenty - eight cases of group B showed obvious sediment, which made the catheter wall rough and change their color, and 11 of them showed fine stone attachment in the cavities and walls of double J catheters. The weight of group A was （0.810 5 ± 0.187 6） g on average, and group B was （ 1.315 9 ± 0.231 1 ） g （ P 〈 0.05 ）. Conclusion Potassium citrate can prevent the stone formation on double J catheters effectively, and it is safe, with less side - effects.