小儿慢性咳嗽检测肺炎支原体抗体的临床意义

Clinical significance of Testing Antibody of Mycoplasma Pneumoniae in Pediatric Patients with Chronic Cough

目的：探讨小儿慢性咳嗽与肺炎支原体（MP）感染的关系。方法：采用金标免疫斑点法，对96例慢性咳嗽患儿（咳嗽组）及50例健康儿童（健康组）进行血清肺炎支原体抗体（MP-IgM）检测。结果：咳嗽组MP-IgM阳性50例，阳性率52．O％，以3～6岁组阳性率最高（74．2％）。健康组阳性4例，阳性率8％，两组阳性率差异有显著性意义（P〈0．01）。结论：MP感染与小儿慢性咳嗽关系密切，在对慢性咳嗽惠儿寻找病因时，应常规进行MP-IgM检测，为临床治疗提供依据。

Objective： To investigate the relationship between mycoplasma pneumoniae infection and chronic cough in children. Methods ：The serum samples of mycoplasma pneumoniae antibody were detected by immunogold-labeling technique in 96 pediatric patients with chronic cough and 50 normal children. Results ：52% （50 of 96 cases）positive rate of MP-IgM was obtained in the serum of patients, with the highest positive rate found in 3-6 year-old-group （74%）. In the control group, them were 4 negative cases （8%） of 50 samples positive rate was shown in control group. The difference was significant difference between the two groups （P 〈 0. 01 ）. Conclusion：There is a close relation between mycoplasma pneumoniae infection and chronic cough in children. Routine test of antibody of mycoplasma pneumoniae in pediatric patients with chronic cough is necessary for providing the clinical evidence to search the cause and give the symptomatic treatment to the patients.