摘要
高脂血症及动脉粥样硬化是引发心脑血管疾病最重要的因素。痰证和瘀证是高脂血症及动脉粥样硬化中最具有典型性的两个证候类型,在常见重要中医证候中也具有代表性,对痰瘀证候实质的研究一直是中医药界关注的焦点。代谢组学等系统生物学手段为高脂血症及动脉粥样硬化痰瘀证候物质基础研究提供了崭新而可靠的技术平台,该文就此做一综述。
Hyperlipidemia and atherosclerosis are the most essential factors to cause cardio -cerebrovascular diseases. Phlegm and blood stasis are the most typical two syndromes of hyperlipidemia and atherosclerosis, and are also the representatives of the common TCM syndromes. Study on the essence of phlegm and blood stasis syndromes is one of the focuses in TCM. As a novel systems biology technique, metabonomics provides a reliable platform for the modem study on the material foundation of phlegm and blood stasis syndromes in hyperlipidemia and atherosclerosis. The application of metabonomics in this field is reviewed in this paper.
出处
《辽宁中医杂志》
CAS
北大核心
2008年第5期684-686,共3页
Liaoning Journal of Traditional Chinese Medicine
基金
北京市自然科学基金资助项目(7072013)
北京市优秀人才培养专项资助项目(20051D0300721)
关键词
高脂血症
动脉粥样硬化
痰瘀
代谢组学
hyperlipidemia
atherosclerosis
phlegm and blood stasis
metabonomics